季凤俊,秦恺,叶飞,陆松华.剑突下入路单孔胸腔镜联合榄香烯治疗自发性气胸的效果及机制.[J].中南医学科学杂志.,2020,(2):134-137.
剑突下入路单孔胸腔镜联合榄香烯治疗自发性气胸的效果及机制
Effect of single-hole thoracoscopy combined with elemene via subxiphoid approach in the treatment of spontaneous pneumothorax and its mechanism
投稿时间:2018-11-15  修订日期:2019-11-18
DOI:10.15972/j.cnki.43-1509/r.2020.02.006
中文关键词:  剑突下入路单孔胸腔镜  榄香烯  自发性气胸  α1-抗胰蛋白酶  皮质醇
英文关键词:single approach thoracoscopy under the inferior gill  elemene  spontaneous pneumothorax  α1-AT  Cor
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作者单位
季凤俊 南通大学附属海安医院胸外科,江苏 南通226600 
秦恺 南通大学附属海安医院胸外科,江苏 南通226600 
叶飞 南通大学附属海安医院胸外科,江苏 南通226600 
陆松华 南通大学附属海安医院胸外科,江苏 南通226600 
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中文摘要:
      探讨榄香烯增加剑突下入路单孔胸腔镜治疗自发性气胸的效果及机制,选择本院诊治的自发性气胸患者130例的临床资料,将给予剑突下入路单孔胸腔镜治疗的患者设为对照组,将给予剑突下入路单孔胸腔镜联合榄香烯治疗的患者设为观察组。结果发现,与对照组比较,观察组的术后引流量、术后留置胸管时间、术后住院时间均显著缩短,VAS评分(视觉模拟评分)显著降低,术后1周皮质醇(Cor)水平显著降低,而α1-抗胰蛋白酶(α1-AT)显著升高,且并发症较少。结果说明,榄香烯能增加剑突下入路单孔胸腔镜治疗自发性气胸的效果不良反应小,其机制可能与改变Cor、α1-AT的表达有关。
英文摘要:
      To investigate the Elemene increased effect of subxiphoid single-port thoracoscopy on spontaneous pneumothorax, 130 patients with spontaneous pneumothorax in our hospital were divided into observation group(treated with single-hole thoracoscopy through subxiphoid approach combined with elemene)and control group(treated with single-hole thoracoscopy through subxiphoid approach), The results showed, compared to the control group, The postoperative drainage volume, postoperative indwelling time and postoperative hospital stay in the observation group were all significantly shortened,the observation group had a significantly smaller VAS, a lower level of Cor and a higher alpha 1-AT, and less complications. Results suggest elemene may increase the effect of Single-hole thoracoscopy via subxiphoid approach on spontaneous pneumothorax, the mechanism is related to decreasing the level of Cor and increasing alpha 1-AT.
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