吴婷,乔娅.利巴韦林联合思连康治疗轮状病毒肠炎合并良性惊厥患者的效果观察.[J].中南医学科学杂志.,2019,(6):597-600.
利巴韦林联合思连康治疗轮状病毒肠炎合并良性惊厥患者的效果观察
Clinical efficacy of combination of ribavirin and Si Lian Kang in the treatment of patients suffered rotavirus enteritis with benign convulsion
投稿时间:2018-11-15  修订日期:2019-06-05
DOI:10.15972/j.cnki.43-1509/r.2019.06.009
中文关键词:  利巴韦林  思连康  轮状病毒  肠炎  惊厥
英文关键词:ribavirin  Si Lian Kang  rotavirus  enteritis  convulsion
基金项目:
作者单位
吴婷 苏州市第九人民医院儿科,江苏 苏州 215200 
乔娅 榆林市儿童医院重症医学科,陕西 榆林 719000 
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中文摘要:
      为观察利巴韦林联合思连康对轮状病毒肠炎合并良性惊厥患儿的治疗效果,选择88例轮状病毒肠炎合并良性惊厥患儿。以利巴韦林联合思连康治疗为观察组,以单用利巴韦林治疗为对照组,结果发现,与对照组相比,观察组组治疗有效率显著升高(59.1% vs 84.1%),住院时间、粪便成型时间和惊厥次数均显著降低,CD4+计数升升高, IL-6、TNF-α、IFN-γ炎症因子水平显著降低。结果提示,利巴韦林联合思连康治疗轮状病毒肠炎伴惊厥患儿,比单用利巴韦林治疗能缩短患者的住院时间,增强临床治疗效果。
英文摘要:
      To observe the therapeutic effect of ribavirin combined with Si Lian Kang on rotavirus enteritis in children with benign convulsion, 88 children with rotavirus enteritis complicated with benign convulsions were selected. They were treated with ribavirin and Si Lian Kang (observation group) and ribavirin alone (control group). Results showed, compared to the control group, the effective rate of observation group was higher (59.1% vs 84.1%), the length of hospital stay, fecal molding time and convulsions were significantly lower, the CD4+ count increased, and the levels of IL-6, TNF-α and IFN-γ inflammatory factors were significantly lower. Treatment of rotavirus enteritis complicated with convulsions with combination of ribavirin and silenkang can shorten hospitalization time and ensure clinical effect.
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