任蓉,石峻.口服米索前列醇联合宫腔吸引管在剖宫产术后无痛人流的应用.[J].中南医学科学杂志.,2019,(6):586-588, 596.
口服米索前列醇联合宫腔吸引管在剖宫产术后无痛人流的应用
Clinical effect of oral misoprostol combined with intrauterine suction tube on painless induced abortion after cesarean section
投稿时间:2019-06-04  修订日期:2019-10-06
DOI:10.15972/j.cnki.43-1509/r.2019.06.006
中文关键词:  米索前列醇  宫腔吸引管  剖宫产  无痛人流  白细胞介素  雌激素
英文关键词:misoprostol  uterine cavity suction tube  cesarean section  painless abortion  interleukin  estrogen
基金项目:
作者单位
任蓉 西安市第九医院妇产科,陕西 西安710000 
石峻 西安市第九医院妇产科,陕西 西安710000 
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中文摘要:
      分析口服米索前列醇联合宫腔吸引管治疗剖宫产术后无痛人流的临床效果及机制。120例患者随机分为对照组(n=60)和观察组(n=60)。对照组患者接受宫腔吸引管处理,观察组患者口服米索前列醇(0.6 mg)后接受宫腔吸引管。结果显示观察组患者的手术时间和苏醒时间明显缩短(P<0.05),术中出血量和异丙酚用量明显减少(P<0.05);观察组患者的宫颈扩张效果总有效率明显升高(P<0.05)而不良反应发生率明显降低(P<0.05);两组患者治疗后血清中白细胞介素1β(IL-1β)和IL-2水平明显升高,且对照组患者的上述白细胞介素水平升高更显著(P<0.05)而雌激素促黄体生成素(Luteotropic hormone,LH)、促卵泡激素(Follicle stimulating horman,FSH)和雌二醇(Estradiol,E2)水平无明显变化(P>0.05)。实验表明口服米索前列醇联合宫腔吸引管治疗剖宫产术后无痛人流临床效果明显,且不引起白细胞介素和雌激素水平的剧烈变化。
英文摘要:
      To study the clinical effect of oral misoprostol combined with uterine cavity suction tube in the treatment of painless induced abortion after cesarean section and its effect on the levels of interleukin and estrogen. 120 patients were randomly divided control group (n=60) and observation group (n=60). The patients in the control group were treated with uterine cavity suction tube. Patients in the observation group received intrauterine suction tube after oral misoprostol (0.6 mg). The results showed that the operation time and recovery time of the patients in the observation group were significantly shortened (P<0.05), and the amount of intraoperative bleeding and propofol consumption were significantly reduced (P<0.05). The total effective rate of cervical dilatation in the observation group was significantly higher (P<0.05) and the incidence of adverse reactions was significantly lower (P<0.05). Serum levels of interleukin-1 beta and interleukin-2 were significantly increased in both groups after treatment. In the control group, the above interleukin levels increased more significantly (P<0.05), while the estrogen levels did not change significantly (P>0.05). So the clinical effect of oral misoprostol combined with uterine cavity suction tube in the treatment of painless induced abortion after cesarean section is obvious, and the level of interleukin and estrogen does not change dramatically.
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