朱子煜,孙文迪,陈丹.软通道技术治疗重症高血压脑出血对患者神经功能和血流动力学水平影响.[J].中南医学科学杂志.,2019,(4):417-420, 424.
软通道技术治疗重症高血压脑出血对患者神经功能和血流动力学水平影响
The effects of soft channel technique on neurological function and hemodynamic level in patients with severe hypertensive intracerebral hemorrhage
投稿时间:2018-10-06  修订日期:2018-11-30
DOI:10.15972/j.cnki.43-1509/r.2019.04.021
中文关键词:  软通道技术  高血压  脑出血  神经功能  血流动力学
英文关键词:soft channel technology  High blood pressure  Cerebral hemorrhage  Neural function  hemodynamics
基金项目:
作者单位
朱子煜 湖北医药学院附属太和医院神经内科,湖北 十堰 442000 
孙文迪 湖北医药学院附属太和医院神经内科,湖北 十堰 442000 
陈丹 武汉科技大学医学院,湖北 武汉 430081 
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中文摘要:
      为了分析软通道技术治疗重症高血压脑出血对患者神经功能和血流动力学水平影响。选取本院收治的83例重症高血压脑出血患者的临床资料进行回顾性分析,分为2组。观察并比较患者术中出血量、手术时间、下床活动时间、住院时间情况,手术前后平均收缩期峰值流速(PSV)、舒张末期血流速度(EDV)、血流速度(Vm)、血管搏动指数(PI)、超氧化物歧化酶(SOD)、丙二醛(MDA)、谷胱肽过氧化物酶(GSH-PX)、脂质过氧化产物(LPO)水平及患者格拉斯哥昏迷指数(GCS)、卒中量表(NIHSS)、日常生活能力量表(BI)评分。结果显示,与常规开颅手术患者相比,采用软通道技术治疗患者术中出血量减少,手术时间、术后下床时间、住院时间缩短;患者PSV、EDV、Vm、PI、SOD、GSH-PX水平升高,MDA、LPO水平降低;患者GCS、BI评分升高,NIHSS评分降低。这说明软通道技术治疗重症高血压脑出血,对患者应激影响小,术后脑血流恢复快,改善神经功能恢复和日常生活能力,值得临床推广应用。
英文摘要:
      To analyze the effects of soft channel technique on the neurological function and hemodynamic level of patients with severe hypertensive intracerebral hemorrhage.The clinical data of 83 patients with severe hypertensive intracerebral hemorrhage admitted in our hospital were retrospectively analyzed and divided into two groups. The blood loss during operation were observed and compared, the time of getting out of bed and the time of hospitalization. Mean peak systolic velocity before and after operation (PSV), end-diastolic velocity (EDV), blood flow velocity (Vm), vascular pulsatility index (PI), superoxide dismutase (SOD), malondialdehyde (MDA), glutathione peroxidase (GSH-PX) lipid peroxidation product (LPO) level and patient lattice Rascox coma Index (GCS), Stroke scale (NIHSS), ADL (BI) score. The results of this study, Compared with the routine craniotomy patients, the amount of intraoperative bleeding was decreased, the operation time, the time of getting out of bed and the hospitalization time were shortened, the PSV, EDV, Vm, PI, SOD, GSH-PX level increased and the MDA-LPO level decreased, the GCS,BI score increased and the NIHSS score decreased. Inconclusion, the soft channel technique for the treatment of severe hypertensive cerebral hemorrhage has little effect on the patients' stress, rapid recovery of cerebral blood flow after the operation, improvement of nerve function recovery and daily living ability, and is worthy of clinical application.
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