| 邓吕红,谭钢,吴恺,王水莲.康柏西普、雷珠单抗单次玻璃体注射治疗渗出型年龄相关性黄斑变性疗效比较.[J].中南医学科学杂志.,2018,(6):657-659, 666. |
| 康柏西普、雷珠单抗单次玻璃体注射治疗渗出型年龄相关性黄斑变性疗效比较 |
| Comparison of single dose injection of Compaq and rezumab in treatment of exudative age-related macular degeneration |
| 投稿时间：2018-08-27 修订日期：2018-10-12 |
| DOI：10.15972/j.cnki.43-1509/r.2018.06.026 |
| 中文关键词: 康柏西普 雷珠单抗 单次注射 年龄相关性黄斑变性 近期视力 远期视力 安全性 |
| 英文关键词:Compaq rezumab single injection age-related macular degeneration recent vision long-term vision safety |
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| 中文摘要: |
| 为比较康柏西普、雷珠单抗单次注射治疗渗出型年龄相关性黄斑变性的效果,本文将渗出型年龄相关性黄斑变性患者48例(50眼)分为康柏西普组(24例25眼)和雷珠单抗组(24例25眼),分别采用单次康柏西普眼用注射液和雷珠单抗玻璃体腔注射治疗。观察比较了两组治疗前后的裸眼视力、眼压、中心视网膜厚度(CRT)、脉络膜新生血管(CNV)面积以及生活质量评分、术后并发症发生率等。结果发现康柏西普、雷珠单抗单次注射治疗渗出型年龄相关性黄斑变性均可有效改善近远期视力、眼压和生活质量,其中康柏西普效果更佳,术后并发症发生率未见增加,安全性良好。 |
| 英文摘要: |
| In order to compare the effect of Compaciclor and Razumab in the treatment of exudative senile macular degeneration (AMD), 48 patients (50 eyes) with exudative AMD were divided into Compaciclor group (245 cases 25 eyes) and Razumab group (24 cases 25 eyes) and had single intravitreal injection of Compaciclor and Razumab respectively. The visual acuity, intraocular pressure, central retinal thickness (CRT), choroidal neovascularization (CNV), quality of life score and postoperative complications before and after treatment were observed and compared between the two groups. The results showed that single injection of Compaciclor and Razumab could effectively improve the short-term and long-term visual acuity, intraocular pressure and quality of life in patients with exudative AMD, in which the Compaciclor was more effective, and its postoperative complications was not increased and the safety was good. |
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