| 李祥，王波，金鑫，李国术，何平平，唐艳艳，张敏，李金凤，欧阳新平.番茄红素改善缺血再灌注模型大鼠认知功能损伤.[J].中南医学科学杂志.,2013,41(6):559-561. |
| 番茄红素改善缺血再灌注模型大鼠认知功能损伤 |
| Lycopene Improves Cognitive Function inIschemia-Reperfusion Rat Models |
| 投稿时间：2013-08-27 |
| DOI： |
| 中文关键词: 番茄红素 创伤性脑外伤 缺血再灌注模型 认知 |
| 英文关键词:lycopene traumatic brain injury ischemia reperfusion model cognitive function |
| 基金项目:湖南省科技厅资助项目（2013FJ3027），湖南省教育厅资助项目（13B103），衡阳市科技局课题（2012KJ22）. |
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| 中文摘要: |
| 目的检测番茄红素（LP）对大脑中动脉栓塞（MCAO）所致缺血再灌注模型大鼠认知功能的影响。 |
| 英文摘要: |
| ObjectiveTo examine effects of Lycopene(LP)on cognitive function in ischemia-reperfusion rat models caused by middle cerebral artery obstruction(MCAO).MethodsMCAO rat models were set up and effects of LP were detected on cognitive function in rat models with Morris water maze and Y maze test.ResultsAverage swimming speed of rats in water maze dropped significantly after MCAO,required training numbers need for avoiding electric shock in Y maze increased significantly.Compared with model group rats,average swimming speed of rats in water maze in low dose LP and high dose LP group increased significantly,training numbers need for avoiding electric shock in Y maze in low dose LP and high dose LP group decreased significantly.ConclusionLycopene improves cognitive function in ischemia-reperfusion rat models. |
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