| 刘梅梅，肖继，王嘉争，王德明.雾化吸入长托宁佐治小儿病毒相关性喘息性支气管炎的疗效观察.[J].中南医学科学杂志.,2011,39(1):92-93. |
| 雾化吸入长托宁佐治小儿病毒相关性喘息性支气管炎的疗效观察 |
| Clinical Adjuvant Effect of Penehyclidine Hydrochloride on Children With Virus-associated Wheezy Bronchitis |
| 投稿时间：2010-09-02 |
| DOI： |
| 中文关键词: 长托宁 喘息性支气管炎 雾化吸入 |
| 英文关键词:penehyclidine hydrochloride wheezy bronchitis atomization inhalation |
| 基金项目: |
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| 中文摘要: |
| 目的观察长托宁雾化吸入辅助治疗小儿病毒相关性喘息性支气管炎的疗效。方法76例病毒相关性喘息性支气管炎患儿随机分为两组，各组患儿在综合治疗的基础上分别雾化吸入长托宁或0.9%生理盐水辅助治疗。结果长托宁雾化组显效19例，有效14例，无效5例；对照组显效11例，有效15例，无效12例。两组差异有统计学意义(χ2=6.992，P<0.05)；同时，长托宁雾化吸入能够使患者肺部哮鸣音消失时间、喘息时间及病程明显缩短，减少住院时间。结论长托宁雾化吸入治疗喘息型支气管炎安全有效，不良反应少，使用方便，值得临床推广使用。 |
| 英文摘要: |
| ObjectiveTo investigate the clinical assisted effect of penehyclidine hydrochloride on children with virus-associated wheezy bronchitis.Methods76 cases of children with virus-associated wheezy bronchitis were randomly divided into two groups，each group were treated by penehyclidine hydrochloride plus 2 mL saline or 0.9% saline atomization inhalation adjuvant therapy after the comprehensive treatment.ResultsIn penehyclidine hydrochloride group，19 cases were markedly effective，14 cases were effective and 5 cases got no effect.In control group，11 cases were markedly effective，15 cases were effective and 12 cases got no effect.The therapeutic effect of penehyclidine hydrochloride treatment was significantly prior to that of control treatment(χ2=6.992，P<0.05).At the same time，penehyclidine hydrochloride could shorten lung wheeze disappearance time，breathing space，the course of disease and reduce length of hospital stay.ConclusionPenehyclidine hydrochloride as an adjuvant treatment for children with virus-associated wheezy bronchitis is safe and effective，with fewer side effects，easy to use and worthy of clinical use. |
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