| 蔡婷,谢水波,吴宇琦,罗志平.阿莫西林的γ辐照降解过程与机理试验研究[J].南华大学学报(自然科学版),2014,28(1):102~107.[CAI Ting,XIE Shui-bo,WU Yu-qi,LUO Zhi-ping.Studies on γ-irradiation-induced-degradation of Amoxicillin in Aqueous Solution[J].Journal of University of South China(Science and Technology),2014,28(1):102~107.] |
| 阿莫西林的γ辐照降解过程与机理试验研究 |
| Studies on γ-irradiation-induced-degradation of Amoxicillin in Aqueous Solution |
| 投稿时间：2013-12-13 |
| DOI： |
| 中文关键词: γ射线 阿莫西林 辐照降解 LC-MS |
| 英文关键词:gamma-ray irradiation amoxicillin degradation LC-MS |
| 基金项目:国家自然科学基金资助项目(11175081);湖南省高校创新平台基金资助项目(13K085);高等学校博士点基金资助项目(20134324110003) |
|
| 摘要点击次数: 643 |
| 全文下载次数: 520 |
| 中文摘要: |
| 探讨了在60Co γ-射线辐照下水中阿莫西林的降解过程,考察了阿莫西林初始浓度、吸收剂量对其辐照降解的影响,利用LC-MS分析了阿莫西林的辐解产物,初步揭示了阿莫西林的降解途径.试验结果表明,γ辐照可有效降解水中的阿莫西林,初始浓度较低有利于阿莫西林的降解.阿莫西林的降解率随吸收剂量增大而增大,G值则随吸收剂量增加而降低,阿莫西林去除率随吸收剂量的变化呈指数关系.当阿莫西林的初始浓度为10 mg/L和100 mg/L,辐照剂量为15 kGy时,其降解率分别为100%和95.14%.阿莫西林经过辐照后主要存在6种辐解产物,其准分子离子质量分别为[M+H]+:278、384、382、336、340、294,初步推断其降解过程主要涉及羟基自由基的氧化. |
| 英文摘要: |
| Amoxicillin was degraded by 60Co gamma-ray irradiation in aqueous solution.The effects of initial concentration of amoxicillin and absorbed dose on degration of amoxicillin were investigated.The identification of radiolytical products has been conducted using high chromatography tandem mass spectrometry and possible pathways for further degration of amoxicillin were studied.Experimental results show that amoxicillin in aqueous solution can be effectively degraded by gamma-ray irradiation,especially in low-concentration.The amoxicillin degradation rate increased with increasing irradiation dose,whereas the G-value decreased,the relationship among amoxicillin removal and absorbed dose can be fit with index curve.Under irradiation dose of 15 kGy,the degration rate reached 100% and 95.14% at amoxicillin of 10 mg/L,100mg/L respectively.After irradiation,six major radiolytical products with [M+H]+278,4,382,6,340,4 were produced,which were detected in several different conditions.Possible pathways for further degration of amoxicillin were studied.Degradation of amoxicillin induced by γ- radiation was mainly ascribed to ·OH oxidation. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
| 关闭 |
|
|
|