邓梨平,程瑞文,李平,曹亚衡,刘羽.经髂内动脉灌注化疗联合125I粒子植入对宫颈癌根治性放疗后复发的临床观察.[J].中南医学科学杂志.,2020,(4):409-412.
经髂内动脉灌注化疗联合125I粒子植入对宫颈癌根治性放疗后复发的临床观察
Clinical observation of recurrent cervical cancer after radical radiotherapywith internal illiac arterial infusion chemotherapy combined with 125I seed implantation
投稿时间:2020-04-24  修订日期:2020-06-11
DOI:10.15972/j.cnki.43-1509/r.2020.04.018
中文关键词:  125I 粒子植入  复发型宫颈癌  动脉灌注化疗  临床疗效
英文关键词:125I seed implantation  recurrent cervical cancer  internal illiac arterial infusion chemotherapy  clinical curative effect
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作者单位
邓梨平 湖南中医药大学第一附属医院血管肿瘤介入科, 湖南 长沙41007 
程瑞文 湖南中医药大学第一附属医院血管肿瘤介入科, 湖南 长沙41007 
李平 湖南中医药大学第一附属医院血管肿瘤介入科, 湖南 长沙41007 
曹亚衡 湖南中医药大学第一附属医院血管肿瘤介入科, 湖南 长沙41007 
刘羽 湖南中医药大学第一附属医院血管肿瘤介入科, 湖南 长沙41007 
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中文摘要:
      探讨经髂内动脉灌注化疗联合125I粒子植入对根治性放疗后宫颈癌复发患者的临床疗效。分析本院收治的分别采用单纯经髂内动脉灌注化疗治疗(单纯灌注化疗组)和联合125I粒子植入治疗(灌注粒子联合组)的宫颈癌复发患者的临床疗效、术后并发症和骨髓抑制数据。灌注粒子联合组临床疗效明显优于单纯灌注化疗组,且没有明显增加并发症和骨髓抑制的发生率。故经髂内动脉灌注化疗联合125I粒子植入能提高根治性放疗后宫颈癌复发患者的临床疗效,值得进一步研究。
英文摘要:
      To investigate the clinical efficacy of internal illiac arterial infusion chemotherapy combined with 125I seed implantation in patients with recurrent cervical cancer after radical radiotherapy. Statistical analysis was respectively performed on the data of clinical efficacy, postoperative complications and bone marrow suppression which were treated with internal illiac arterial infusion chemotherapy (only infusion chemotherapy group) and combined 125I seeds implantation (infusion particle combination group) in our hospital. The clinical efficacy of the infusion particle combination group was better than that of the only infusion chemotherapy group, and there was no significant increase in the incidence of complications and bone marrow suppression. Therefore, internal illiac arterial infusion chemotherapy combined with 125I seed implantation can improve the clinical efficacy of patients with recurrence cervical cancer after radical radiotherapy, which is worthy of further research.
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