| 吴鹏,陶婷,施芳,王湘东,孙中平,王佐,吴仕元.孕期胎盘生长因子动态检测联合高危因素对子痫前期的预测价值.[J].中南医学科学杂志.,2020,(4):399-402. |
| 孕期胎盘生长因子动态检测联合高危因素对子痫前期的预测价值 |
| Predictive value of dynamic detection of placental growth factor during pregnancy and high risk factors for pre-eclampsia |
| 投稿时间：2020-03-25 修订日期：2020-06-04 |
| DOI：10.15972/j.cnki.43-1509/r.2020.04.015 |
| 中文关键词: 胎盘生长因子 高危因素 子痫前期 预测 |
| 英文关键词:placental growth factor high risk factors pre-eclampsia prediction |
| 基金项目: |
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| 摘要点击次数: 605 |
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| 中文摘要: |
| 探讨胎盘生长因子(PLGF)在不同孕周单次检测与动态检测结合高危因素对子痫前期(PE)的预测价值,选取2019年1月至12月期间在本院行产检并分娩的PE孕妇52例为研究对象(研究组),同期抽取在本院行产前检查并分娩的非PE孕妇113例进行对照(对照组),根据建卡的孕周不同,分别于孕12~15周、16~20周、＞20周后进行了PLGF单次检测或动态检测,并进行了高危因素筛查。结果显示,妊娠期糖尿病、孕前体重指数≥24、年龄≥35岁、辅助生殖技术妊娠、高血压病史等高危因素研究组明显高于对照组(P＜0.05)；研究组PLGF检测异常率明显高于对照组(P＜0.05),动态检测异常率高于孕12~15周及孕16~20周单次检测异常率(P＜0.05)。表明不同孕周PLGF的动态检测联合高危因素筛查对PE有一定预测价值。 |
| 英文摘要: |
| To investigate the predictive value of placental growth factor (PLGF) during pregnancy with single test and dynamic test combined with high-risk factors for pre-eclampsia. A total of 52 pre-eclampsia patients who underwent prenatal examination and delivered in our hospital from January 1,2019 to December 31,2019 were selected as the research subjects (study group). 113 non-preeclampsia pregnant women who were examined and delivered in our hospital were compared (control group). The gestational weeks were different according to the card. They were pregnant for 12-15 weeks, 16-20 weeks, and ＞20 weeks. Later, a single or dynamic detection of PLGF was performed, and a screening of high-risk factors for pre-eclampsia was performed. The results showed that gestational diabetes high-risk factors such as BMI ≥24, age ≥35 years, pregnancy assisted reproductive technology, and history of hypertension were significantly higher in the study group than in the control group (P＜0.05). The abnormal rate of PLGF detection in the research group was significantly higher than that in the control group (P＜0.05), and the abnormal detection rate in the dynamic group was higher than the single detection abnormal rate in 12-15 weeks of pregnancy and 16-20 weeks of pregnancy (P＜0.05). It shows that the dynamic detection of PLGF at different gestational weeks combined with screening for high risk factors has certain predictive value for PE. |
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