曾雪莉,王爱红.性激素三项在子宫肌瘤患者血清变化的意义研究.[J].中南医学科学杂志.,2020,(1):49-51, 87.
性激素三项在子宫肌瘤患者血清变化的意义研究
Significance of estrogen level in serum of patients with uterine leiomyoma
投稿时间:2019-01-14  修订日期:2019-03-06
DOI:10.15972/j.cnki.43-1509/r.2020.01.014
中文关键词:  子宫肌瘤  雌激素(E2)  卵泡刺激素(FSH)  黄体生成素(LH)
英文关键词:uterine fibroids  estrogen (E2)  follicle stimulating hormone (FSH)  luteinizing hormone (LH)
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作者单位
曾雪莉 湖北省随州市曾都医院妇科, 湖北 随州 441300 
王爱红 湖北省随州市曾都医院妇科, 湖北 随州 441300 
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中文摘要:
      观察子宫肌瘤患者血清性激素三项(E2、FSH、LH)水平变化,并分析其临床意义。以在本院接受治疗的子宫肌瘤患者(观察组)和体检的健康女性(对照组)为观察对象,比较两组血清雌激素(E2)、卵泡刺激素(FSH)、黄体生成素(LH)水平的差异,比较不同特征子宫肌瘤患者E2、FSH、LH水平的不同,分析影响子宫肌瘤患者E2、FSH、LH水平的因素。结果显示,与对照组比较,观察组患者的血清E2水平升高,FSH、LH水平降低于;肌瘤数目≥2个、肌瘤直径≥5 cm的子宫肌瘤患者的E2水平较高,FSH、LH水平较低,不同年龄、生育史、合并高血压和合并糖尿病患者的E2、FSH、LH水平无明显差别;多重逐步回归分析说明肌瘤数目和直径是影响患者E2、FSH、LH水平的因素。结果说明,子宫肌瘤患者血清E2水平较高,FSH、LH水平较低,且受肌瘤直径和数目的影响。
英文摘要:
      To observe the serum levels of three sex hormones (E2, FSH, LH) in patients with uterine fibroids and its clinical significance. The patients with uterine fibroids who were treated in our hospital were selected as observation objects, and healthy women who were examined in our hospital at the same time were selected as controls. The differences of serum estrogen (E2), follicle stimulating hormone (FSH) and luteinizing hormone (LH) levels between the two groups were observed. The differences of E2, FSH and LH levels in patients with different features of uterine fibroids were compared. The results showed that compared with the control group, the serum E2 level of the observation group increased, the FSH and LH levels decreased; the uterine fibroids with the number of fibroids ≥ 2 and the diameter of the fibroids ≥ 5 cm had higher E2 levels, FSH, LH levels were low, and there were no significant differences in E2, FSH, and LH levels between patients of different ages, birth history, hypertension, and diabetes mellitus; multiple stepwise regression analysis indicated that the number and diameter of fibroids were factors affecting E2, FSH, and LH levels in patients. The results showed that patients with uterine fibroids had higher serum E2 levels, lower FSH and LH levels, and were affected by the diameter and number of fibroids.
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