| 高一飞,谭春淼,张佰爽,王贺田.心率变异性联合NLR对急性心肌梗死患者PCI术后远期预后的预测价值.[J].中南医学科学杂志.,2026,(1):51-54. |
| 心率变异性联合NLR对急性心肌梗死患者PCI术后远期预后的预测价值 |
| Predictive value of heart rate variability combined with NLR for long-term prognosis in patients with acute myocardial infarction after PCI |
| 投稿时间:2025-04-03 修订日期:2025-09-27 |
| DOI:10.15972/j.cnki.43-1509/r.2026.01.011 |
| 中文关键词: 心率变异性 NLR AMI 经皮冠状动脉介入术 预后 |
| 英文关键词:heart rate variability NLR acute myocardial infarction percutaneous coronary intervention prognosis |
| 基金项目:国家卫生健康委“十四五”规划全国重点课题(YYWS4388) 作者简介:高一飞,硕士,主治医师,研究方向为冠状动脉介入、心律失常介入治疗,E-mail为sd55fsdw2@163.com。 |
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| 中文摘要: |
| 目的探讨心率变异性联合中性粒细胞-淋巴细胞比值(NLR)对急性心肌梗死(AMI)患者经皮冠状动脉介入(PCI)术后远期预后的预测价值。 方法回顾性选取行PCI术的AMI患者102例,根据术后随访12个月是否发生主要不良心血管事件(MACE)分为无MACE组和MACE组。比较两组心率变异性指标[24 h内正常RR间期标准差(SDNN)、RR间期平均值标准差(SDANN)、低频成分(LF)、高频成分(HF)、PNN50]、NLR。采用ROC曲线分析心率变异性指标以及NLR对患者预后的预测价值。 结果MACE组年龄、发病至就诊时间、吸烟史、高脂血症史、心率高于无MACE组(P<0.05),其他指标两组比较差异无显著性(P>0.05)。与术前比较,两组术后SDNN、SDANN、LF、HF、PNN50均升高,NLR均降低(P<0.05);且无MACE组较MACE组变化更为显著(P<0.05)。各指标联合对术后患者预后的预测价值高于单独指标(P<0.001)。 结论心率变异性联合NLR可预测AMI患者PCI术后远期MACE事件的发生。 |
| 英文摘要: |
| AimTo explore the predictive value of heart rate variability (HRV) combined with neutrophil-lymphocyte ratio (NLR) for long-term prognosis in patients with acute myocardial infarction (AMI) after percutaneous coronary intervention (PCI). MethodsA total of 102 AMI patients undergoing PCI were retrospectively enrolled and divided into a non-MACE group and a MACE group according to the occurrence of major adverse cardiovascular events (MACE) during 12 months of follow-up. HRV indices (SDNN, SDANN, LF, HF, PNN50) and NLR were compared between the two groups. Receiver operating characteristic (ROC) curve analysis was used to evaluate the predictive value of HRV indices and NLR for prognosis. ResultsThe MACE group had higher age, onset-to-admission time, proportion of smoking history, hyperlipidemia history, and heart rate compared with the non-MACE group (P<0.05), while other indicators showed no significant differences (P>0.05). Compared with preoperative values, both groups showed increased SDNN, SDANN, LF, HF, and PNN50, and decreased NLR after surgery (P<0.05), with more significant changes in the non-MACE group than those in the MACE group (P<0.05). The combined predictive value of all indicators for postoperative prognosis was higher than that of any single indicator (P<0.001). ConclusionHeart rate variability combined with NLR can predict the occurrence of MACE in AMI patients after PCI during long-term follow-up. |
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