| 陈多军,蒋文韬,朱家双,张敏,彭沪.PCT联合SII对脓毒症患者病情转归的预测价值.[J].中南医学科学杂志.,2026,(1):48-50, 78. |
| PCT联合SII对脓毒症患者病情转归的预测价值 |
| The predictive value of PCT combined with SII for disease outcomes of sepsis patients |
| 投稿时间：2025-02-26 修订日期：2025-10-28 |
| DOI：10.15972/j.cnki.43-1509/r.2026.01.010 |
| 中文关键词: 脓毒症 降钙素原 全身免疫炎症指数 病情转归 预测价值 |
| 英文关键词:sepsis PCI SII disease outcomes predictive value |
| 基金项目:国家自然科学基金资助项目(82272184) 作者简介:陈多军,主治医师,研究方向为重症感染及相关疾病的诊治,E-mail为cdjchenduojun@163.com。通信作者彭沪,博士,主任医师,研究方向为重症感染及相关疾病的诊治,E-mail为pohjiju@126.com。 |
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| 中文摘要: |
| 目的分析降钙素原(PCT)联合全身免疫炎症指数(SII)对脓毒症患者病情转归的预测价值。 方法回顾性分析本院收治的81例脓毒症患者的临床资料,根据入院是否发生休克分为脓毒症组(未休克)24例与脓毒症休克组57例；按治疗28天后病情转归分为预后不良组(死亡或放弃治疗后失访)20例与预后良好组(出院或转出重症监护室)61例。比较脓毒症休克组与脓毒症组、预后良好组与预后不良组入院时、入院3天、入院7天PCT、SII水平。采用ROC曲线分析脓毒症患者入院时PCT、SII对疾病转归的预测效能。 结果入院时、入院3天、入院7天时,脓毒症休克组、预后不良组PCT、SII分别高于脓毒症组、预后良好组(P＜0.05)。预后不良组脓毒症休克患者的占比高于预后良好组(P＜0.05)。ROC曲线分析结果显示,入院时PCT、SII及两者联合预测脓毒症患者预后不良的AUC值分别为0.522、0.545及0.892。 结论脓毒症患者入院时PCT、SII水平与其病情严重程度及预后有关,联合检测对患者病情转归具有较高的预测效能。 |
| 英文摘要: |
| AimTo analyze the predictive value of procalcitonin (PCT) combined with the systemic immune inflammatory index (SII) for the disease outcomes of sepsis patients. MethodsThe clinical data of 81 sepsis patients admitted to our hospital were retrospectively analyzed. They were divided into a sepsis group (24 cases without shock) and a septic shock group (57 cases) based on whether shock occurred upon admission; According to the outcome after 28 days of treatment, they were divided into the poor outcome group (20 cases,death or loss to follow-up after abandoning treatment) and the good outcome group (61 cases,discharge or transfer to the intensive care unit). The PCT and SII levels were compared between the septic shock group and the sepsis group, as well as between the good outcome group and the poor outcome group at admission, 3 days after admission, and 7 days after admission.ROC curve analysis was used to evaluate the predictive efficacy of PCT and SII for disease outcomes in sepsis patients upon admission. ResultsAt admission, 3 days after admission, and 7 days after admission, PCT and SII were higher in the septic shock group and poor outcome group than those in the sepsis group and good outcome group, respectively (P＜0.05). The proportion of septic shock patients in the poor outcome group was higher than that in the good outcome group (P＜0.05). The ROC curve analysis results showed that the AUC of PCT, SII, and their combined prediction of poor prognosis in sepsis patients at admission were 0.522,0.545, and 0.892, respectively. ConclusionThe levels of PCT and SII in sepsis patients upon admission are related to the severity and prognosis of their conditions, and combined detection has a high predictive power for the patient's disease outcome. |
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