| 麻婷婷,张富杰,郑亚丽,杨娜.瑞马唑仑复合瑞芬太尼在第三磨牙拔除术镇静中的应用效果.[J].中南医学科学杂志.,2025,(6):1085-1088. |
| 瑞马唑仑复合瑞芬太尼在第三磨牙拔除术镇静中的应用效果 |
| Efficacy of remimazolam combined with remifentanil for sedation in patients undergoing third molar extraction |
| 投稿时间：2025-02-28 修订日期：2025-09-27 |
| DOI：10.15972/j.cnki.43-1509/r.2025.06.036 |
| 中文关键词: 瑞马唑仑 瑞芬太尼 第三磨牙拔除术 镇静 血流动力学 |
| 英文关键词:remimazolam remifentanil third molar extraction sedation hemodynamics |
| 基金项目:廊坊市科技支撑计划项目(2023013048) |
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| 中文摘要: |
| 目的探讨瑞马唑仑复合瑞芬太尼在第三磨牙拔除术患者镇静中的应用效果。 方法选取90例拟行第三磨牙拔除术患者为研究对象,随机均分为对照组(丙泊酚复合瑞芬太尼麻醉)和观察组(瑞马唑仑复合瑞芬太尼麻醉)。比较两组血流动力学、血氧饱和度、麻醉效果、苏醒质量及并发症情况。 结果观察组意识消失时间、意识恢复时间短于对照组,术后恢复质量评估量表(PQRS)评分高于对照组(P＜0.05)。与苏醒时比较,苏醒后30 min、术后2 h时两组视觉模拟量表(VAS)疼痛评分升高,Ramsay镇静评分降低；苏醒时、苏醒后30 min、术后2 h时观察组VAS疼痛评分低于对照组,Ramsay镇静评分高于对照组(P＜0.05)。与T1比较,两组T2、T3平均动脉压、心率及血氧饱和度降低(P＜0.05)；与对照组比较,观察组T2、T3平均动脉压和心率以及T3血氧饱和度较高(P＜0.05)。观察组并发症发生率低于对照组(P＜0.05)。 结论在第三磨牙拔除术患者中应用瑞马唑仑复合瑞芬太尼麻醉方案,其镇静效果确切,且并发症少,安全性较高。 |
| 英文摘要: |
| AimTo evaluate the efficacy of remimazolam combined with remifentanil for sedation in patients undergoing third molar extraction. MethodsA total of 90 patients scheduled for third molar extraction were randomly divided into a control group (anesthetized with propofol combined with remifentanil) and an observation group (anesthetized with remimazolam combined with remifentanil). Hemodynamics, oxygen saturation, anesthetic efficacy, recovery quality, and complications were compared between the two groups. ResultsThe time to loss of consciousness and recovery time were shorter in the observation group than those in the control group, while the postoperative quality recovery scale (PQRS) score was higher (P＜0.05). Compared with the time of awakening, visual analogue scale (VAS) pain scores increased at 30 min after awakening and 2 h after surgery, while Ramsay sedation scores decreased. At awakening, 30 min after awakening, and 2 h after surgery, the observation group had lower VAS pain scores and higher Ramsay sedation scores compared with the control group (P＜0.05). Compared with T1, mean arterial pressure, heart rate, and oxygen saturation decreased at T2 and T3 in both groups (P＜0.05). The observation group showed higher mean arterial pressure and heart rate at T2 and T3, as well as higher oxygen saturation at T3, compared with the control group (P＜0.05). The incidence of complications was lower in the observation group than that in the control group (P＜0.05). ConclusionRemimazolam combined with remifentanil provides reliable sedation with fewer complications and high safety in patients undergoing third molar extraction. |
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