| 杨廷桂,林瑜娜,庄莉莉,张登庆.冠状动脉CT血管成像对冠心病患者冠状动脉狭窄及斑块易损性的评估价值.[J].中南医学科学杂志.,2025,(6):1081-1084. |
| 冠状动脉CT血管成像对冠心病患者冠状动脉狭窄及斑块易损性的评估价值 |
| Value of coronary artery CT angiography in the assessment of coronary artery stenosis and plaque vulnerability in patients with coronary heart disease |
| 投稿时间：2025-02-12 修订日期：2025-09-20 |
| DOI：10.15972/j.cnki.43-1509/r.2025.06.035 |
| 中文关键词: 冠状动脉CT血管成像 冠心病 冠状动脉狭窄 斑块易损性 |
| 英文关键词:coronary artery CT angiography coronary heart disease coronary artery stenosis plaque vulnerability |
| 基金项目:泉州市科技计划项目(2022N027S) |
|
| 摘要点击次数: 49 |
| 全文下载次数: 28 |
| 中文摘要: |
| 目的探究冠状动脉CT血管成像(CCTA)对冠心病患者冠状动脉狭窄及斑块易损性的评估价值。 方法选取冠心病患者100例,均进行CCTA和冠状动脉血管造影(CAG)检查。根据CCTA检查结果将患者分为高危斑块组(n＝56)和非高危斑块组(n＝44)。以CAG结果为金标准,分析CCTA判断冠状动脉狭窄的灵敏度、特异度、阳性预测值和阴性预测值。应用ROC曲线分析心外膜脂肪组织体积、心外膜脂肪组织密度对高危斑块的预测效能。 结果CCTA诊断冠状动脉狭窄的灵敏度为95.74%,特异度为96.27%,准确度为96.06%,阳性预测值为94.27%,阴性预测值为97.24%,与金标准CAG检查的一致性高(P＜0.05)。CCTA检查和CAG检查冠状动脉狭窄程度情况比较,差异无显著性(P＝0.931)。高危斑块组心外膜脂肪组织体积、心外膜脂肪组织密度均高于非高危斑块组(P＜0.05)。ROC曲线分析显示,心外膜脂肪组织密度较体积对高危斑块预测效能高。 结论CCTA能较好地判断冠状动脉斑块引起的狭窄,心外膜脂肪组织密度预测高危斑块具有较高效能。 |
| 英文摘要: |
| AimTo explore the value of coronary artery CT angiography (CCTA) in evaluating coronary artery stenosis and plaque vulnerability in patients with coronary heart disease (CHD). MethodsA total of 100 CHD patients underwent both CCTA and coronary angiography (CAG) were selected. Based on CCTA findings, patients were divided into a high-risk plaque group (n＝56) and a non-high-risk plaque group (n＝44). Using CAG as the gold standard, the sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of CCTA for diagnosing coronary stenosis were analyzed. ROC curves were used to evaluate the predictive efficacy of epicardial adipose tissue (EAT) volume and density for high-risk plaques. ResultsThe sensitivity, specificity, accuracy, PPV, and NPV of CCTA for diagnosing coronary stenosis were 95.74%, 96.27%, 96.06%, 94.27%, and 97.24%, respectively, with high consistency with CAG (P＜0.05). No significant difference was found between CCTA and CAG in assessing the degree of coronary stenosis (P＝0.931). The EAT volume and density were significantly higher in the high-risk plaque group than those in the non-high-risk plaque group (P＜0.05). ROC analysis indicated that EAT density had higher predictive efficacy for high-risk plaques than EAT volume. ConclusionCCTA demonstrates good performance in evaluating coronary stenosis caused by plaques, and EAT density shows high predictive efficacy tto identify high-risk plaques. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
| 关闭 |
|
|
|