| 储志娟,谢湘,王翔.口腔白斑患者抑郁情绪的影响因素分析.[J].中南医学科学杂志.,2025,(6):984-986, 1108. |
| 口腔白斑患者抑郁情绪的影响因素分析 |
| Analysis of influencing factors of depression in patients with oral leukoplakia |
| 投稿时间：2024-10-19 修订日期：2025-03-25 |
| DOI：10.15972/j.cnki.43-1509/r.2025.06.010 |
| 中文关键词: 口腔白斑 抑郁 焦虑 危险因素 |
| 英文关键词:oral leukoplakia depression anxiety risk factors |
| 基金项目:国家自然科学基金资助项目(81870767) 作者简介:储志娟,主管护师,研究方向为口腔黏膜疾病护理,E-mail为chuzhijuan123456@126.com。通信作者王翔,博士,主任医师,研究方向为口腔黏膜疾病的诊治,E-mail为yuwx999@sina.com。 |
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| 中文摘要: |
| 目的探讨口腔白斑(OLK)患者抑郁情绪的发生情况及其影响因素。 方法选取OLK患者115例作为OLK组,并选取同期健康体检者115例作为对照组。收集所有研究对象基线资料,采用贝克抑郁量表(BDI)评估抑郁情绪发生情况。将存在抑郁情绪的OLK患者纳入抑郁组(30例),其余为非抑郁组(85例)。通过单因素及多因素分析OLK患者抑郁情绪的影响因素。 结果OLK组抑郁情绪发生率及BDI分值均高于对照组(P＜0.05)。抑郁组中女性、月收入低于5 000元、存在上皮异常增生、病变大小≥2 cm及贝克焦虑量表(BAI)≥45分的患者比例及VAS评分高于非抑郁组(P＜0.05)。Logistic回归分析显示,性别、月收入、上皮异常增生、病变大小、VAS评分及BAI评分为OLK患者抑郁情绪发生的危险因素(P＜0.05)。 结论OLK患者易出现抑郁情绪,其发生与性别、月收入、上皮异常增生、病变大小、VAS评分及BAI评分密切相关。 |
| 英文摘要: |
| AimTo investigate the occurrence and influencing factors of depression in patients with oral leukoplakia (OLK). MethodsA total of 115 OLK patients were selected as the OLK group, while 115 healthy subjects undergoing physical examination during the same period were included as the control group. Baseline data were collected, and the Beck Depression Inventory (BDI) was used to assess depressive symptoms. OLK patients with depression were assigned to a depression group (n＝30), while the others were assigned to a non-depression group (n＝85). Univariate and multivariate analyses were performed to identify influencing factors for depression. ResultsThe incidence of depression and BDI scores in the OLK group were higher than those in the control group (P＜0.05). The proportions of females, those with a monthly income below 5000 yuan, epithelial dysplasia, lesion size ≥2 cm, and BAI score ≥45 were higher in the depression group than those in the non-depression group, along with higher VAS score (P＜0.05). Logistic regression analysis indicated that gender, monthly income, epithelial dysplasia, lesion size, VAS score, and BAI score were risk factors for depression in OLK patients (P＜0.05). ConclusionOLK patients are prone to depression, and its occurrence is associated with gender, monthly income, epithelial dysplasia, lesion size, VAS score, and BAI score. |
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