| 秦志刚,赵芳,王志伟,高泽宇,刘向阳.慢性鼻-鼻窦炎伴鼻息肉患者鼻内镜术后复发的影响因素及风险模型构建.[J].中南医学科学杂志.,2025,(1):154-157. |
| 慢性鼻-鼻窦炎伴鼻息肉患者鼻内镜术后复发的影响因素及风险模型构建 |
| Influencing factors of recurrence in patients with CRSwNP after nasal endoscopy and construction of risk model |
| 投稿时间：2024-05-09 修订日期：2024-12-07 |
| DOI：10.15972/j.cnki.43-1509/r.2025.01.038 |
| 中文关键词: 慢性鼻-鼻窦炎伴鼻息肉 鼻内镜术 复发 影响因素 风险模型 [ |
| 英文关键词:CRSwNP nasal endoscopy recurrence influencing factor risk model |
| 基金项目:大同市科技计划项目(KJX0356) |
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| 中文摘要: |
| 目的分析慢性鼻-鼻窦炎伴鼻息肉(CRSwNP)患者鼻内镜术后复发的影响因素,并构建术后复发风险模型。 方法收集行鼻内镜术的CRSwNP患者300例,按4∶1随机分为验证组和建模组；建模组按复发情况分为复发组(64例)和未复发组(176例),比较各组临床基本资料。Logistic多因素回归分析术后复发的影响因素,公式法构建术后复发风险的预测模型,采用ROC曲线评估模型的预测能力。 结果复发组年龄、变应性鼻炎比例、支气管哮喘比例、长期使用鼻减充血剂比例、EOS型鼻息肉比例、术前视觉模拟评分、术前Lund-Mackay评分、术后接受综合治疗比例和术后感染比例等与未复发组比较,差异均有统计学意义(P＜0.05)。支气管哮喘、长期使用鼻减充血剂、EOS型鼻息肉、术前Lund-Mackay评分高、术后未接受综合治疗和术后感染是术后复发的危险因素(P＜0.05)。成功构建CRSwNP患者鼻内镜术后复发风险的预测模型,该风险预测模型对CRSwNP患者鼻内镜术后复发风险具有一定预测价值(P＜0.05)。 结论成功建立CRSwNP患者鼻内镜术后复发的风险预测模型,将之应用于临床有助于识别复发高风险人群。 |
| 英文摘要: |
| AimTo analyze the influencing factors of recurrence in patients with chronic rhinosinusitis with nasal polyps (CRSwNP) after nasal endoscopy, and to construct the risk model of postoperative recurrence. MethodsA total of 300 patients with CRSwNP undergoing nasal endoscopy were enrolled and randomly divided into verification group and modeling group at a ratio of 4∶1. According to presence or absence of recurrence, patients in modeling group were divided into recurrence group (64 cases) and non-recurrence group (176 cases). The clinical baseline data in different groups were compared. The influencing factors of postoperative recurrence were analyzed by multivariate Logistic analysis. The prediction model for postoperative recurrence risk was constructed by formula method, and its predictive efficiency was evaluated by ROC curves. ResultsThere were significant differences in age, proportions of allergic rhinitis, bronchial asthma, long-term usage of nasal decongestants and EOS nasal polyps, preoperative visual analog scale and Lund-Mackay scores, proportions of postoperative comprehensive treatment and infection between recurrence group and non-recurrence group (P＜0.05). Bronchial asthma, long-term usage of nasal decongestants, EOS nasal polyps, high preoperative Lund-Mackay score, no postoperative comprehensive treatment and postoperative infection were risk factors of postoperative recurrence (P＜0.05). The prediction model for postoperative recurrence risk was constructed successfully, which showed certain predictive value (P＜0.05). ConclusionThe prediction model for recurrence risk is constructed successfully in patients with CRSwNP after nasal endoscopy. The clinical application of prediction model is beneficial to identify the group with high recurrence risk. |
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