| 杨海涛,王冠,邱良贤.HbA1C联合血脂指标对老年2型糖尿病患者发生心脑血管事件的预测价值评估.[J].中南医学科学杂志.,2024,(6):1003-1005. |
| HbA1C联合血脂指标对老年2型糖尿病患者发生心脑血管事件的预测价值评估 |
| Evaluation of the predictive value of HbA1C combined with lipid indicators for occurring cardiovascular and cerebrovascular events in elderly patients with type 2 diabetes |
| 投稿时间：2024-01-26 修订日期：2024-10-18 |
| DOI：10.15972/j.cnki.43-1509/r.2024.06.032 |
| 中文关键词: 老年 2型糖尿病 HbA1C TC TG LDLC HDLC 心脑血管事件 |
| 英文关键词:old age T2DM HbA1C TC TG LDLC HDLC cardiovascular and cerebrovascular events |
| 基金项目:深圳市年度科技计划项目(201003069) 作者简介:杨海涛,博士,主任医师,研究方向为介入心脏病学,E-mail为hxr_cct@163.com。 |
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| 中文摘要: |
| 目的评估糖化血红蛋白(HbA1c)联合血脂指标对老年2型糖尿病(T2DM)患者发生心脑血管事件的预测价值。 方法将156例老年T2DM患者根据是否发生心脑血管事件分为观察组(发生心脑血管事件)和对照组(未发生心脑血管事件)。比较两组HbA1C和血脂指标总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDLC)和低密度脂蛋白胆固醇(LDLC)水平。采用多因素Logistic回归分析心脑血管事件发生的影响因素。ROC曲线分析HbA1C和血脂指标水平对老年T2DM发生心脑血管事件的预测价值。 结果观察组HbA1C、TC、TG、LDLC高于对照组,而HDLC低于对照组(P＜0.05)。HbA1C、TC、TG、LDLC是老年T2DM患者心脑血管事件发生的影响因素(P＜0.05)。HbA1C联合血脂指标预测老年T2DM患者发生心脑血管事件具有一定的价值。 结论HbA1C联合血脂指标对老年T2DM患者发生心脑血管事件具有一定的预测价值。 |
| 英文摘要: |
| AimTo evaluate the predictive value of glycosylated hemoglobin (HbA1c) combined with blood lipid indicators for occurring cardiovascular and cerebrovascular events in elderly patients with type 2 diabetes mellitus (T2DM). Methods156 elderly patients with T2DM were divided into the observation group (with cardiovascular and cerebrovascular events) and the control group (without cardiovascular and cerebrovascular events) according to whether the patients had cardiovascular and cerebrovascular events. The levels of HbA1C and blood lipid indicators total cholesterol (TC), triglycerides (TG), high-density lipoprotein cholesterol (HDLC), and low-density lipoprotein cholesterol (LDLC) between two groups were compared. Multivariate Logistic regression analysis was used to investigate the influencing factors of cardiovascular and cerebrovascular events. ROC curve was used to analyze the predictive value of HbA1C and blood lipid levels on the occurrence of cardiovascular and cerebrovascular diseases in elderly patients with T2DM. ResultsThe observation group had higher HbA1C, TC, TG, LDLC and lower HDLC than the control group (P＜0.05). HbA1C, TC, TG and LDLC were the influencing factors of occurring cardiovascular and cerebrovascular events in elderly patients with T2DM (P＜0.05). HbA1C combined with lipid indicators had certain value in predicting cardiovascular and cerebrovascular events in elderly patients with T2DM. ConclusionHbA1C combined with blood lipid indicators has a certain predictive value for occurring cardiovascular and cerebrovascular events in elderly patients with T2DM. |
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