曾华勇.CTP对脑梗死伴颈动脉狭窄患者脑血流动力学变化的评估价值.[J].中南医学科学杂志.,2024,(6):988-991.
CTP对脑梗死伴颈动脉狭窄患者脑血流动力学变化的评估价值
Evaluation value of CTP on hemodynamic changes in patients with cerebral infarction and carotid stenosis
投稿时间:2024-04-16  修订日期:2024-06-27
DOI:10.15972/j.cnki.43-1509/r.2024.06.028
中文关键词:  CTP  脑梗死  颈动脉狭窄  血流动力学变化
英文关键词:CTP  cerebral infarction  carotid artery stenosis  hemodynamic changes
基金项目:四川省卫计委科研课题(16PJ400) 作者简介:曾华勇,主管技师,研究方向为临床影像学,E-mail为15228335369@163.com。
作者单位E-mail
曾华勇 江油市人民医院,四川江油621700 e-mail为15228335369@163.com 
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中文摘要:
      目的探究CT灌注成像(CTP)对脑梗死伴颈动脉狭窄患者血流动力学变化的评估价值。 方法选择本院接收的脑梗死伴颈动脉狭窄患者112例纳入观察组,另选50例未发生脑梗死的颈动脉狭窄患者纳入对照组。两组患者均接受CTP检查,观察组根据颈动脉狭窄程度分为轻度狭窄组(42例)、中度狭窄组(21例)、重度狭窄组(22例)、闭塞组(27例)。比较观察组与对照组间以及观察组不同亚组间患者的血流动力学指标[脑血容量(CBV)、脑血流量(CBF)、平均通过时间(MTT)、达峰时间(TTP)]水平。 结果与对照组比较,观察组的CBV、CBF水平降低,MTT、TTP升高(P<0.05)。重度狭窄组和闭塞组患者的颞叶、额叶、基底节区CBV和CBF水平低于轻度狭窄组和中度狭窄组,MTT和TTP水平高于轻度狭窄组和中度狭窄组(P<0.05)。 结论CTP对脑梗死合并颈动脉狭窄患者的血流动力学变化情况评估具有一定价值,不同程度的颈动脉狭窄患者间的血流动力学参数存在显著差异。
英文摘要:
      AimTo explore the value of CT perfusion imaging (CTP) in assessing hemodynamic changes in patients with cerebral infarction and carotid stenosis. Methods112 patients with cerebral infarction and carotid artery stenosis admitted to our hospital were selected as the observation group, and 50 patients with carotid artery stenosis who did not experience cerebral infarction were selected as the control group. Both groups of patients underwent CTP examination. The observation group was divided into mild stenosis group (42 cases), moderate stenosis group (21 cases), severe stenosis group (22 cases), and occlusion group (27 cases) based on the degree of carotid artery stenosis. The hemodynamic indicators of cerebral blood volume (CBV), cerebral blood flow (CBF), mean transit time (MTT), and time to peak (TTP) between the observation group and the control group, as well as these parameters among different subgroups of the observation group, were compared. ResultsCompared with control patients, CBV, CBF levels were decreased and MTT and TTP were increased in the observation group (P<0.05). The CBV, CBF levels in the temporal lobe, frontal lobe, and basal ganglia of patients with severe stenosis and occlusion were lower than those in the mild stenosis and moderate stenosis groups, while the MTT and TTP levels were higher than those in the mild stenosis and moderate stenosis groups (P<0.05). ConclusionCTP has certain value in evaluating the hemodynamic changes of patients with cerebral infarction combined with carotid artery stenosis, and there are significant differences in hemodynamic parameters among patients with different degrees of carotid artery stenosis.
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