| 朱慧敏,刘星婧,谷慧平.心率变异性联合TyG指数对糖尿病肾病患者MACE的预测价值.[J].中南医学科学杂志.,2024,(6):911-914. |
| 心率变异性联合TyG指数对糖尿病肾病患者MACE的预测价值 |
| Predictive value of heart rate variability combined with TyG for MACE in patients with diabetes nephropathy |
| 投稿时间：2024-05-10 修订日期：2024-10-27 |
| DOI：10.15972/j.cnki.43-1509/r.2024.06.008 |
| 中文关键词: 心率变异性 甘油三酯-葡萄糖指数 糖尿病肾病 主要不良心血管事件 预测价值 |
| 英文关键词:heart rate variability triglyceride-glucose index diabetic kidney disease major adverse cardiovascular events predictive value |
| 基金项目:江苏省自然科学基金青年基金项目(BK20241684) 作者简介:朱慧敏,硕士,住院医师,研究方向为心电诊断,E-mail为zhuhuimin812@126.com。通信作者谷慧平,主任医师,研究方向为动态心电诊断,E-mail为1290237301@qq.com |
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| 中文摘要: |
| 目的探讨心率变异性(HRV)联合甘油三酯-葡萄糖(TyG)指数对糖尿病肾病(DKD)患者主要不良心血管事件(MACE)的预测价值。 方法选取DKD患者182例,根据随访1年是否发生MACE分为MACE组(n＝73)与非MACE组(n＝109)。比较两组入院时HRV指标[标准差(SDNN)、相邻NN间期标准差(SDANN)]与TyG指数。采用受试者工作特征(ROC)曲线评估HRV、TyG指数对发生MACE的预测价值,采用多因素Logistic回归分析探讨DKD患者发生MACE的影响因素。 结果单因素分析发现,MACE组患者DKD病程、吸烟史比例高于非MACE组(P＜0.05),其他指标两组间比较差异无显著性(P＞0.05)。与非MACE组比较,MACE组SDNN、SDANN降低,TyG指数升高(P＜0.05)。多因素Logistic回归分析显示,吸烟史、SDNN、SDANN、TyG指数是影响DKD患者发生MACE的危险因素(P＜0.05)。HRV指标联合TyG指数对DKD患者发生MACE具有良好的预测价值(P＜0.05)。 结论HRV指标与TyG指数联合检测对DKD患者发生MACE有较好的预测效能。 |
| 英文摘要: |
| AimTo explore the predictive value of heart rate variability (HRV) combined with triglyceride glucose (TyG) index for major adverse cardiovascular events (MACE) in patients with diabetes nephropathy (DKD). Methods182 patients with DKD were selected and divided into MACE group (n＝73) and non-MACE group (n＝109) based on whether MACE occurred during the 1-year follow-up. The HRV index (SDNN,SDANN) and TyG index between two groups upon admission were compared. The receiver operating characteristic (ROC) curve was used to evaluate the predictive value of HRV and TyG for the occurrence of MACE. Multiple Logistic regression analysis was used to explore the influencing factors of MACE in DKD patients. ResultsUnivariate analysis revealed that the MACE group had a higher proportion of DKD duration and smoking history than the non-MACE group (P＜0.05), while there was no significant difference in other indicators between the two groups (P＞0.05). Compared with the non-MACE group, the MACE group showed a decrease in SDNN and SDANN, and an increase in TyG index (P＜0.05). Multivariate Logistic regression analysis showed that smoking history, SDNN, SDANN, and TyG index were risk factors for MACE in DKD patients (P＜0.05). The combination of HRV index and TyG index has a good predictive value for MACE in DKD patients (P＜0.05). ConclusionThe combined detection of HRV index and TyG index has a good predictive power for MACE in DKD patients. |
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