| 何克强,辛浩.血清3-NT、cTnT、心功能与STEMI患者介入治疗后左心室重构的关系.[J].中南医学科学杂志.,2024,(5):768-771. |
| 血清3-NT、cTnT、心功能与STEMI患者介入治疗后左心室重构的关系 |
| Relationship between serum 3-NT, cTnT, cardiac function and left ventricular remodeling in STEMI patients after interventional therapy |
| 投稿时间：2024-03-14 修订日期：2024-08-25 |
| DOI：10.15972/j.cnki.43-1509/r.2024.05.018 |
| 中文关键词: 3-NT 急性ST段抬高心肌梗死 cTnT 心功能 左心室重构 |
| 英文关键词:3-NT acute ST-segment elevation myocardial infarction cTnT cardiac function left ventricular remodeling |
| 基金项目:陕西省科学技术研究发展计划项目(2021K17-01) |
|
| 摘要点击次数: 0 |
| 全文下载次数: 0 |
| 中文摘要: |
| 目的探讨血清3-硝基氨基酸(3-NT)、心肌肌钙蛋白T(cTnT)、心功能与急性ST段抬高心肌梗死(STEMI)患者介入治疗后左心室重构的关系。 方法选取85例STEMI患者,按介入治疗后是否出现左心室重构分为观察组(n＝42)和对照组(n＝43)。比较两组介入治疗前后血清3-NT、cTnT水平及介入治疗1周后心功能情况。分析STEMI患者介入治疗后左心室重构的影响因素,以及各因素对发生左心室重构的预测价值。 结果观察组体质指数、收缩压、舒张压、空腹血糖、总胆固醇、低密度脂蛋白胆固醇、同型半胱氨酸水平明显高于对照组(P＜0.05)。与治疗前相比,治疗后两组血清3-NT、cTnT升高,且观察组高于对照组(P＜0.05)。PCI术治疗1周后,观察组左心室舒张期末容积(LVEDV)高于对照组,左室射血分数(LVEF)低于对照组(P＜0.05)。血清3-NT与cTnT、LVEDV呈正相关,3-NT与LVEF呈负相关(P＜0.05)。总胆固醇、低密度脂蛋白胆固醇、3-NT是STEMI患者PCI术后发生左心室重构的危险因素(P＜0.05)。3-NT对预测左心室重构具有良好的效能(P＜0.05)。 结论3-NT是STEMI患者PCI术后发生左心室重构的危险因素,其对预测左心室重构具有良好的效能。 |
| 英文摘要: |
| AimTo investigate the relationship between serum 3-nitroamino acid (3-NT), cardiac troponin T (cTnT), and cardiac function and left ventricular remodeling in patients with acute ST segment elevation myocardial infarction (STEMI) after interventional therapy. Methods85 STEMI patients were selected and divided into observation group (n＝42) and control group (n＝43) based on whether left ventricular remodeling occurred after interventional treatment. Serum levels of 3-NT and cTnT before and after intervention therapy, as well as the cardiac function after one week of intervention therapy, between the two groups of patients, were compared. The influencing factors of left ventricular remodeling in STEMI patients after interventional treatment, and the predictive value of each factor for occurrence of left ventricular remodeling, were analyzed. ResultsThe body mass index, systolic blood pressure, diastolic blood pressure, fasting blood glucose, total cholesterol, low-density lipoprotein cholesterol, and homocysteine levels in the observation group were significantly higher than those in the control group (P＜0.05). Compared with the parameters before treatment, the serum 3-NT and cTnT levels in both groups increased after treatment, and the observation group was higher than the control group (P＜0.05). After one week of PCI treatment, the left ventricular ejection fraction (LVEDV) of the observation group was higher than that of the control group, and the left ventricular ejection fraction (LVEF) was lower than that of the control group (P＜0.05). Serum 3-NT is positively correlated with cTnT and LVEDV, while 3-NT is negatively correlated with LVEF (P＜0.05).Total cholesterol, low-density lipoprotein cholesterol, and 3-NT were risk factors for left ventricular remodeling in STEMI patients after PCI (P＜0.05). 3-NT has good efficacy in predicting left ventricular remodeling (P＜0.05). Conclusion3-NT is a risk factor of left ventricular remodeling in STEMI patients after PCI, and it has good efficacy in predicting left ventricular remodeling. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
| 关闭 |
|
|
|