| 崔强,王凡,程华才,丰斌.不同b值ADC对前列腺癌患者术后Gleason评分的预测效果.[J].中南医学科学杂志.,2024,(4):669-672. |
| 不同b值ADC对前列腺癌患者术后Gleason评分的预测效果 |
| Predictive efficacy of DWI with different b-values on postoperative Gleason scores in prostate cancer patients |
| 投稿时间：2023-07-11 修订日期：2023-12-28 |
| DOI：10.15972/j.cnki.43-1509/r.2024.04.042 |
| 中文关键词: 磁共振成像 前列腺癌 Gleason评分 表观扩散系数 扩散加权成像 |
| 英文关键词:magnetic resonance imaging prostate cancer Gleason score apparent diffusion coefficient diffusion weighted imaging |
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| 中文摘要: |
| 目的探究磁共振成像(MRI)不同b值扩散加权成像(DWI)预测前列腺癌患者术后Gleason评分的临床价值。 方法选取穿刺并接受根治术治疗的62例前列腺癌患者,根据术后Gleason评分分为中高危组(≥7分,n＝39)和低危组(＜7分,n＝23)。采用ROC分析不同b值对前列腺癌患者术后Gleason评分的预测效能。 结果中高危组患者前列腺体积小于低危组患者(P＜0.05)。前列腺癌患者DWI图均表现为高信号,但中高危组不同b值的表观扩散系数(ADC)均小于低危组(P＜0.05)。ADCb50、ADCb400和ADCb800预测前列腺癌患者术后Gleason评分的AUC分别为0.690、0.703、0.775,3者对于前列腺癌患者术后Gleason评分是否≥7分均有一定的预测效能,其中b值为800 s/mm2时特异度和灵敏度最高,分别为87.2%和60.9%。 结论MRI对于前列腺癌患者术后Gleason评分是否≥7分有一定的预测效能,其中b值为800 s/mm2时特异度和灵敏度最高。 |
| 英文摘要: |
| AimTo evaluate the clinical value of diffusion weighted imaging (DWI) magnetic resonance imaging (MRI) with different b-values in predicting postoperative Gleason scores in prostate cancer patients. MethodsSixty-two prostate cancer patients who accepted puncture biopsy and radical prostatectomy were selected and divided into low-grade group (＜7 points, n＝39) and intermediate-to-high-grade group (≥ 7 points, n＝23) based on the postoperative Gleason scores. ROC was plotted to evaluate the predictive efficacy of different b values on postoperative Gleason scores in patients with prostate cancer. ResultsThe prostate volume in intermediate-to-high-grade group was smaller than that in low-grade group (P＜0.05). The lesions of the patients showed as hyperintense signal on DWI, while the apparent diffusion coefficient (ADC) for different b-values were all smaller in intermediate-to-high-grade group than in low grade group (P＜0.05). The AUC of ADCb50, ADCb400 and ADCb800 for predicting postoperative Gleason scores in prostate cancer patients were 0.690,0.703, and 0.775, respectively. All of them had certain predictive efficacy for postoperative Gleason scores ≥ 7 in prostate cancer patients, while the b value of 800 s/mm2 provided the highest predictive specificity and sensitivity, reaching 87.2% and 60.9%, respectively. ConclusionMRI is of certain value in predicting the postoperative Gleason score ≥ 7 in prostate cancer patients, with the highest specificity and sensitivity at a b-value of 800 s/mm2. |
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