黄鑫波,陈镔,陈柱林,朱东仪,黄勇.脑血流超声、ONSD评估CPR患者神经功能的临床价值.[J].中南医学科学杂志.,2024,(3):428-431. |
脑血流超声、ONSD评估CPR患者神经功能的临床价值 |
Clinical value of cerebral blood flow ultrasound and ONSD for nerve function evaluation in CPR patients |
投稿时间:2023-04-27 修订日期:2024-01-18 |
DOI:10.15972/j.cnki.43-1509/r.2024.03.028 |
中文关键词: 脑血流动力学 视神经鞘直径 心肺复苏 神经功能 [ |
英文关键词:cerebral hemodynamics optic nerve sheath diameter cardio-pulmonary resuscitation nerve function |
基金项目:广西高校中青年教师科研基础能力提升项目(2022KY1931) |
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中文摘要: |
目的探讨脑血流超声联合视神经鞘直径(ONSD)评估心肺复苏(CPR)患者神经功能的临床价值。方法选取行CPR术后昏迷患者100例,根据预后分为预后良好组和预后不良组。比较两组临床资料、术后脑脊液压力以及术后1、3、7天超声参数。分析脑脊液压力与超声参数的相关性、影响CPR患者神经功能预后的因素以及超声参数评估CPR患者神经功能预后的价值。 结果与预后良好组比较,预后不良组CPR时间、机械通气时间增加;院内心脏骤停占比降低、术后1天搏动指数(PI)、阻力指数(RI)、术后3、7天ONSD、PI、RI升高;术后1天平均血流速度(Vm)、术后3、7天收缩期血流速度(Vs)、舒张期末血流速度(Vd)、Vm降低;术后脑脊液压力升高(P<0.05)。术后脑脊液压力与ONSD、RI、PI、Vm均具相关性(P<0.05)。CPR时间、脑脊液压力、ONSD、RI、PI、Vm是神经功能预后的独立影响因素(P<0.05)。术后3天双侧ONSD、Vm、RI、PI对CPR患者神经功能预后具有良好的预测价值(P<0.05)。 结论超声动态监测脑血流和ONSD可有效评估CPR患者神经功能预后。 |
英文摘要: |
AimTo explore clinical value of cerebral blood flow ultrasound combined with optic nerve sheath diameter (ONSD) for nerve function evaluation in patients undergoing cardio-pulmonary resuscitation (CPR). MethodsA total of 100 patients with coma after CPR were enrolled. According to different prognosis results, they were divided into good prognosis group and poor prognosis group. The clinical data, postoperative cerebrospinal fluid pressure and ultrasound parameters at 1 d, 3 d and 7 d after surgery were compared between the two groups. The correlation between CSF pressure and ultrasound parameters, influencing factors of prognosis, and evaluation value of ultrasound parameters for nerve function prognosis were analyzed. ResultsCompared with good prognosis group, CPR time and mechanical ventilation time were increased in poor prognosis group. Proportion of nosocomial cardiac arrest proportion was decreased, pulsative index (PI) and resistance index (RI) at 1 d after surgery, as well as ONSD, PI and RI at 3 d and 7 d after surgery, were increased. Mean flow velocity (Vm) at 1 d after surgery, and peak systolic velocity (Vs), end diastolic velocity (Vd) and Vm at 3 d and 7 d after surgery, were decreased. And postoperative postoperative cerebrospinal fluid pressure was increased (P<0.05). The postoperative postoperative cerebrospinal fluid pressure was correlated with ONSD, RI, PI and Vm (P<0.05). CPR time, postoperative cerebrospinal fluid pressure, ONSD, RI, PI and Vm were independent risk factors for nerve function prognosis (P<0.05). Bilateral ONSD, Vm, RI and PI at 3 d after surgery were of good predictive value for nerve function prognosis of CPR patients (P<0.05). ConclusionThe dynamic monitoring of cerebral blood flow ultrasound and ONSD can effectively evaluate the prognosis of nerve function in coma patients after CPR. |
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