| 邓茂文,贾鹏,吴虹.UABGA和NBNA评分预测新生儿HIE短期预后的价值.[J].中南医学科学杂志.,2024,(2):254-257. |
| UABGA和NBNA评分预测新生儿HIE短期预后的价值 |
| Value of UABGA and NBNA score in predicting short-term prognosis of HIE |
| 投稿时间：2023-04-24 修订日期：2023-09-28 |
| DOI：10.15972/j.cnki.43-1509/r.2024.02.024 |
| 中文关键词: 新生儿 缺氧缺血性脑病 脐动脉血气分析 神经行为评分 预后 [ |
| 英文关键词:neonate HIE UABGA NBNA prognosis |
| 基金项目:宜宾市科技基金项目(2021SF02) |
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| 中文摘要: |
| 目的探讨脐动脉血气分析(UABGA)和神经行为测定(NBNA)评分对新生儿缺氧缺血性脑病(HIE)短期预后的预测价值。 方法随机选取分娩的足月新生儿1 877例,确诊HIE者36例,以HIE患儿为观察组,随机抽取同期正常新生儿50例为对照组,比较两组脐动脉血气指标及出生后2~3天、12~14天、26~28天NBNA评分。36例HIE患儿随访6个月,用Gesell发育量表评估其短期预后,回顾性分析预后良好组和预后不良组的脐动脉血气分析指标和NBNA评分情况,采用ROC分析相关指标对HIE短期预后的预测价值。 结果HIE组和对照组脐动脉血气分析指标[pH、氧分压(PO2)、二氧化碳分压(PCO2)、碱剩余(BE)和碳酸氢根(HCO－3)]和3个时间点NBNA评分差异均有统计学意义(P＜0.05)。预后良好组和预后不良组的脐动脉血气分析指标(pH、PO2、PCO2和BE)和2个时间点(12~14天及26~28天)NBNA评分差异有统计学意义(P＜0.05)；pH、PO2、12~14天和26~28天NBNA评分对新生儿HIE短期预后有预测价值。 结论pH、PO2、12~14天和26~28天NBNA评分能作为预测HIE患儿短期预后的重要指标。 |
| 英文摘要: |
| AimTo explore the predictive value of umbilical artery blood gas analysis (UABGA) and neurobehavioral (NBNA) score in the short-term prognosis of neonatal hypoxic-ischemic encephalopathy (HIE). Methods1 877 full-term newborns delivered were randomly selected, and 36 cases were diagnosed with HIE. Taking HIE newborns as the observation group and 50 normal children in the same period as the control group, the umbilical artery blood gas indexes and NBNA scores at three time points (day 2－3, day 12－14 and day 26－28 after birth) were compared between the two groups. 36 newborns with HIE were followed up for 6 month and the short-term prognosis was evaluated by Gesell development scale. The umbilical artery blood gas analysis indexes and NBNA scores at three time points in the good prognosis group and poor prognosis group were analyzed retrospectively. The predictive value of relevant indexes in the short-term prognosis of HIE was analyzed by ROC. ResultsThere were significant differences in umbilical artery blood gas analysis indexes [pH, oxygen pressure (PO2), carbon dioxide pressure (PCO2), base excess (BE) and bicarbonate (HCO－3)] and NBNA scores at three time points between HIE group and normal control group (P＜0.05). There was significant difference in umbilical artery blood gas analysis indexes (pH, PO2, PCO2 and BE) and NBNA score at two time points (12－14 d and 26－28 d) between good prognosis group and poor prognosis group (P＜0.05). The AUC of ROC curve of pH, PO2,12－14 days and 26－28 days were 0.763,0.712,0.761 and 0.758, respectively. ConclusionpH, PO2, day 12－14 and day 26－28 NBNA scores can be used as important indexes to predict the short-term prognosis of HIE. |
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