殷艳丽,王俊英,柏淯文,许伟.Nd:YAG激光与Er:YAG激光辅助治疗重度牙周炎的疗效分析.[J].中南医学科学杂志.,2024,(1):128-130, 145.
Nd:YAG激光与Er:YAG激光辅助治疗重度牙周炎的疗效分析
Efficacy analysis of Nd:YAG laser and Er:YAG laser assisted treatment for severe periodontitis
投稿时间:2023-04-12  修订日期:2023-12-08
DOI:10.15972/j.cnki.43-1509/r.2024.01.031
中文关键词:  Nd:YAG激光  Er:YAG激光  重度牙周炎  龈沟液 [
英文关键词:Nd:YAG laser  Er:YAG laser  severe periodontitis  gingival crevicular fluid
基金项目:
作者单位E-mail
殷艳丽 襄阳市口腔医院牙周病科,湖北襄阳441000 e-mail为346035034@qq.com,e-mail为xyxw9803@163.com 
王俊英 襄阳市口腔医院牙周病科,湖北襄阳441000  
柏淯文 襄阳市口腔医院牙周病科,湖北襄阳441000  
许伟 襄阳市口腔医院牙周病科,湖北襄阳441000 e-mail为346035034@qq.com,e-mail为xyxw9803@163.com 
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中文摘要:
      目的比较Nd:YAG激光和Er:YAG激光辅助治疗重度牙周炎的疗效,分析其对龈沟液基质金属蛋白酶(MMP)、前列腺素E2(PGE2)和炎症因子水平的影响。 方法选取108例重度牙周炎患者,随机均分为Nd:YAG组和Er:YAG组。比较两组临床疗效、牙周健康指标、龈沟液相关指标。 结果两组治疗总有效率比较差异无显著性(P>0.05)。与治疗前比较,治疗后两组菌斑指数(PLI)、牙周袋深度(PD)、龈沟出血指数(BI)、临床附着水平(CAL)降低,且Er:YAG组CAL较Nd:YAG组降低更显著,Nd:YAG组BI较Er:YAG组降低更显著(P<0.05)。与治疗前比较,两组治疗后MMP-8、MMP-9、PGE2、炎症因子水平均降低(P<0.05),但治疗后两组间差异无显著性(P>0.05)。 结论Nd:YAG激光和Er:YAG激光对重度牙周炎均有良好的辅助治疗效果,但Er:YAG激光改善牙周组织附着更明显,Nd:YAG激光止血效果更好。
英文摘要:
      AimTo compare the efficacy of Nd:YAG laser and Er:YAG laser assisted treatment for severe periodontitis, and analyze their effects on the levels of matrix metalloproteinase (MMP), prostaglandin E2 (PGE2), and inflammatory factors in gingival crevicular fluid. Methods108 patients with severe periodontitis were selected and randomly divided into Nd:YAG group and Er:YAG group. The clinical efficacy, periodontal health indicators, and gingival crevicular fluid related indicators between two groups were compared. ResultsThere was no significant difference in the total effective rate between the two groups (P>0.05).Compared with before treatment, PLI, PD, BI, and CAL were decreased in both groups after treatment, and the decrease in CAL in the Er:YAG group was more significant than that in the Nd:YAG group, the decrease in BI in the Nd:YAG group was more significant than that in the Er:YAG group (P<0.05). Compared with before treatment, MMP-8, MMP-9, PGE2, inflammatory factors levels in both groups after treatment were decreased (P<0.05), but there was no difference between the two groups (P>0.05). ConclusionBoth Nd:YAG laser and Er:YAG laser have good adjuvant treatment effects on severe periodontitis, but Er:YAG laser improves periodontal tissue attachment more significantly, and Nd:YAG laser has better hemostatic effect.
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