| 何海刚,李勇,施盛锋,黄凯荣.血清hs-cTn、MYO、NT-proBNP与AMI后心力衰竭患者心室重塑的关系.[J].中南医学科学杂志.,2023,(6):960-962. |
| 血清hs-cTn、MYO、NT-proBNP与AMI后心力衰竭患者心室重塑的关系 |
| Relationship between serum hs-cTn, MYO and NT-proBNP and ventricular remodeling in patients with heart failure after AMI |
| 投稿时间：2022-11-30 修订日期：2023-09-10 |
| DOI：10.15972/j.cnki.43-1509/r.2023.06.040 |
| 中文关键词: 急性心肌梗死 心力衰竭 心室重塑 hs-cTn MYO NT-proBNP [ |
| 英文关键词:acute myocardial infarction heart failure ventricular remodeling hs-cTn MYO NT-proBNP |
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| 中文摘要: |
| 目的探究急性心肌梗死(AMI)后心力衰竭患者血清超敏肌钙蛋白(hs-cTn)、肌红蛋白(MYO)、氨基末端B型脑钠肽前体(NT-proBNP)水平与心室重塑的关系。 方法选择AMI后心力衰竭患者103例,按NYHA心功能分级或是否心室重塑分为Ⅱ级组、Ⅲ级组、Ⅳ级组或心室重塑组、非心室重塑组。比较各组血清hs-cTnT、hs-cTnI、MYO、NT-proBNP水平,分析其与心功能分级的相关性,以及对心室重塑的诊断价值。结果患者hs-cTnT、hs-cTnI、MYO、NT-proBNP水平心室重塑组高于非心室重塑组,且随心功能分级增加而升高,其水平与心功能分级呈正相关(P＜0.05)。血清hs-cTnT、hs-cTnI、MYO、NT-proBNP联合检测对AMI后心力衰竭患者心室重塑预测效能最高(P＜0.05)。 结论血清hs-cTnT、hs-cTnI、MYO、NT-proBNP联合检测对AMI后心力衰竭患者心室重塑具有预测价值。 |
| 英文摘要: |
| AimTo explore the relationship between levels of serum high sensitivity cardiac troponin (hs-cTn), myoglobin (MYO) and N-terminal pro-B-type natriuretic peptide (NT-proBNP) and ventricular remodeling in patients with heart failure after acute myocardial infarction (AMI). Methods103 patients with heart failure after AMI were selected. According to the NYHA cardiac function grading or presence or absence of ventricular remodeling, the patients were classified into grade Ⅱ group, grade Ⅲ group and grade Ⅳ group or ventricular/non-ventricular remodeling group. The levels of serum hs-cTnT, hs-cTnI, MYO and NT-proBNP were compared among the groups, and the correlation between cardiac function grading and diagnostic value on ventricular remodeling was analyzed. ResultsThe levels of serum hs-cTnT, hs-cTnI, MYO and NT-proBNP in ventricular remodeling group were higher than those in non-ventricular remodeling group. The above levels were increased with the increase of cardiac function grading, and were positively correlated with cardiac function grading (P＜0.05). The combined detection of serum hs-cTnT, hs-cTnI, MYO and NT-proBNP had the highest predictive efficiency on ventricular remodeling in patients with heart failure after AMI (P＜0.05). ConclusionThe combined detection ofserum hs-cTnT, hs-cTnI, MYO and NT-proBNP has diagnostic value on ventricular remodeling in patients with heart failure after AMI. |
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