| 韩婷羽,陈丽玲.玻璃体腔注射康柏西普联合玻璃体切割术对增殖型糖尿病视网膜病变的疗效.[J].中南医学科学杂志.,2023,(6):890-893. |
| 玻璃体腔注射康柏西普联合玻璃体切割术对增殖型糖尿病视网膜病变的疗效 |
| Curative effect of intravitreal injection of Conbercept combined with vitrectomy on proliferative diabetic retinopathy |
| 投稿时间：2023-05-28 修订日期：2023-08-04 |
| DOI：10.15972/j.cnki.43-1509/r.2023.06.021 |
| 中文关键词: 玻璃体腔注射 玻璃体切割术 康柏西普 增殖型糖尿病视网膜病变 黄斑中心凹厚度 [ |
| 英文关键词:intravitreal injection vitrectomy Conbercept proliferative diabetic retinopathy central macular thickness |
| 基金项目:湖南省卫生健康委科研课题(202107020686) |
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| 中文摘要: |
| 目的探讨玻璃体腔注射康柏西普联合玻璃体切割术(PPV)治疗增殖型糖尿病视网膜病变(PDR)的临床效果。 方法将就诊的84例PDR患者采用随机数字表法分为观察组和对照组各42例42眼。观察组行玻璃体腔注射康柏西普联合PPV手术治疗,对照组患者仅行PPV手术治疗。对比两组PDR患者治疗前、PPV术后1个月最佳矫正视力(BCVA)、黄斑中心凹厚度(CMT)、眼压的变化情况和PPV术后1个月玻璃体出血情况。 结果PPV术后1个月观察组患者BCVA优于对照组(P＜0.05),CMT低于对照组(P＜0.05)；而两组术前术后眼压的差异无显著性(P＞0.05),PPV术后1个月观察组玻璃体积血发生率低于对照组(P＜0.05)。 结论玻璃体腔注射康柏西普联合PPV手术可有效改善PDR患者的视力,减少黄斑区水肿,减少手术后并发症。 |
| 英文摘要: |
| AimTo study the effect of intravitreal injection of Conbercept combined with vitrectomy on proliferative diabetic retinopathy. MethodsA total of 84 patients with PDR treated were selected. Based on the control principle, they were randomly divided into the observation group and the control group, with 42 cases in each group. The observation group was treated with Conbercept combined with PPV through intravitreal injection, while the control group was treated with PPV only. The best corrected visual acuity (BCVA), macular foveal thickness (CMT), intraocular pressure and vitreous hemorrhage at one month after PPV were compared between the two groups before treatment and after PPV. ResultsBCVA in one mouth observation group after PPV was significantly better than that in control group (P＜0.05), and CMT was significantly lower than control group (P＜0.05). There was no significant difference in intraocular pressure between the two groups (P＞0.05), ad the incidence of vitreous hemorrhage in the one mouth observation group after PPV was significantly lower than that in the control group (P＜0.05). ConclusionIntravitreal injection of Conbercept combined with PPV can effectively improve the visual acuity of PDR patients, reduce macular edema and reduce postoperative complications. |
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