| 杜志云,李书秀,许海娟,史亦男,王欢.无创间歇正压通气模式对新生儿呼吸窘迫综合征患儿肺换气功能、预后的影响.[J].中南医学科学杂志.,2023,(5):760-762. |
| 无创间歇正压通气模式对新生儿呼吸窘迫综合征患儿肺换气功能、预后的影响 |
| Influence of non-invasive intermittent positive pressure ventilation mode on pulmonary ventilation function and prognosis in children with neonatal respiratory distress syndrome |
| 投稿时间：2022-07-06 修订日期：2022-11-22 |
| DOI：10.15972/j.cnki.43-1509/r.2023.05.035 |
| 中文关键词: 无创间歇正压通气 新生儿呼吸窘迫综合征 氧合指数 弥散指数 预后 [ |
| 英文关键词:NIPPV NRDS oxygenation index diffusion index prognosis |
| 基金项目:秦皇岛市科学技术研究与发展计划项目(202101A128) |
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| 中文摘要: |
| 目的探讨无创间歇正压通气(NIPPV)模式对新生儿呼吸窘迫综合征(NRDS)患儿氧合指数(OI)及弥散指数、预后的影响。 方法选择轻中度(NRDS Ⅰ-Ⅲ级)新生儿呼吸窘迫综合征患儿95例作为研究对象,随机将其分为观察组50例和对照组45例。观察组采用NIPPV模式,对照组采用经鼻持续气道正压通气(N-CPAP)模式。比较两组治疗成功率、呼吸机使用时间、氧疗时间、住院时间、治疗前和治疗24 h后的弥散指数与OI,比较两组并发症以及预后情况。 结果观察组治疗成功率高于对照组(P＜0.05)。观察组呼吸机使用时间、氧疗时间、住院时间均短于对照组(P＜0.05)。治疗24 h后,两组弥散指数与OI均明显升高,且观察组高于对照组(P＜0.05)。观察组肺部感染、慢性肺支气管发育不良、鼻黏膜损伤发生率低于对照组(P＜0.05)。 结论无创间歇正压通气模式治疗新生儿呼吸窘迫综合征成功率高,在改善患儿氧合指数、弥散指数及预后方面具有显著效果,适合推广应用。 |
| 英文摘要: |
| AimTo investigate the effect of non-invasive intermittent positive pressure ventilation (NIPPV) mode on oxygenation index (OI), diffusion index and prognosis in children with neonatal respiratory distress syndrome (NRDS). MethodsA total of 95 children with mild to moderate (NRDS Ⅰ-Ⅲ) neonatal respiratory distress syndrome were diagnosed, and were divided into observation group (n＝50) and the control group (n＝45). The observation group was treated with non-invasive intermittent positive pressure ventilation (NIPPV) mode, and the control group was treated with nasal continuous positive airway pressure (N-CPAP) mode. The treatment success rate, duration of ventilator use, oxygen therapy and hospital stay, diffusion index and OI before and 24 hours after treatment were compared between the two groups. The complications and prognosis were compared between the two groups. ResultsThe treatment success rates of the observation group was higher than that in the control group (P＜0.05). The duration of ventilator use, oxygen therapy and hospital stay in the observation group were significantly shorter than those in the control group (P＜0.05). The diffusion index and OI of the two groups were significantly increased, and were higher in the observation group than in the control group (P＜0.05). ConclusionThe non-invasive intermittent positive pressure ventilation mode has a high success rate in the treatment of neonatal respiratory distress syndrome, and has significant effects in improving the oxygenation index, diffusion index and prognosis of children. Furthermore, it is suitable for popularization and application. |
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