| 张文琼,浦钰虹.自适应式生物反馈疗法联合小麦纤维复合低聚果糖治疗OOC的临床观察.[J].中南医学科学杂志.,2023,(5):699-702. |
| 自适应式生物反馈疗法联合小麦纤维复合低聚果糖治疗OOC的临床观察 |
| Clinical observation on self-adaptive biofeedback therapy combined with wheat fiber composite fructooligosaccharide in treating OOC |
| 投稿时间：2022-07-25 修订日期：2023-08-20 |
| DOI：10.15972/j.cnki.43-1509/r.2023.05.018 |
| 中文关键词: OOC 自适应式生物反馈疗法 小麦纤维复合低聚果糖 [ |
| 英文关键词:OOC self-adaptive biofeedback therapy wheat fiber composite fructooligosaccharide |
| 基金项目:上海市杨浦区创新医药科技计划项目(202100459) |
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| 中文摘要: |
| 目的观察自适应式生物反馈疗法联合小麦纤维复合低聚果糖治疗出口梗阻型便秘(OOC)的临床疗效。 方法选取64例OOC患者随机均分为对照组(自适应式生物反馈)和观察组(自适应式生物反馈+小麦纤维复合低聚果糖)。比较两组临床疗效、临床症状评分、肛管直肠动力学指标[肛管静息压(ARP)、直肠最大耐受容量(RMTV)、肛管收缩压(AMCP)]、盆底表面肌电情况、肠道菌群变化,以及不良反应情况和停止治疗后复发率。 结果观察组总有效率高于对照组(P＜0.05)。治疗后,两组各临床症状评分、ARP、RMTV、AMCP、复发率、肠杆菌和肠球菌水平均低于治疗前,且观察组低于对照组；两组前基线、快速收缩、持续收缩、耐久收缩、后基线、双歧杆菌和乳酸杆菌水平均高于治疗前,且观察组高于对照组(P＜0.05)。两组不良反应比较差异无显著性(P＞0.05)。 结论自适应式生物反馈疗法联合小麦纤维复合低聚果糖治疗OCC疗效显著,值得临床推广应用。 |
| 英文摘要: |
| AimTo observe the clinical efficacy of self-adaptive biofeedback therapy combined with wheat fiber composite fructooligosaccharide in the treatment of outlet obstructive constipation (OOC). Methods64 patients with OOC were randomly and evenly divided into control group (self-adaptive biofeedback) and observation group (self-adaptive biofeedback+wheat fiber composite fructooligosaccharide). The clinical efficacy, and clinical symptoms scores, anorectal dynamic indicators [anal canal resting pressure (ARP), rectal maximum tolerated volume (RMTV), anal maximum contraction pressure (AMCP)], pelvic floor surface electromyography and intestinal flora changes, adverse reactions and recurrence rate after treatment discontinuation were compared between the two groups. ResultsThe total effective rate in the observation group was higher than that in the control group (P＜0.05). After treatment, the scores of clinical symptoms, ARP, RMTV, AMCP, recurrence rate and counts of Enterobacter and Enterococcus in both groups were lower than those before treatment, and the above indicators in the observation group were lower compared with those in the control group (P＜0.05). After treatment, the precoxal line, rapid contraction, sustained contraction, durable contraction and postcoxal line and counts of Bifidobacterium and Lactobacillus in the two groups of patients were all higher than those before treatment, and the above indicators in the observation group were higher compared to the control group (P＜0.05). There were no significant differences in the adverse reactions between the two groups (P＞0.05). ConclusionSelf-adaptive biofeedback therapy combined with wheat fiber composite fructooligosaccharide has a significant efficacy in the treatment of OCC, and it is worthy of clinical promotion and application. |
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