| 果鑫园,张宁,柯密密,孙莹.能谱CT灌注成像在早期脑梗死病情程度鉴别中的应用.[J].中南医学科学杂志.,2023,(4):558-560, 574. |
| 能谱CT灌注成像在早期脑梗死病情程度鉴别中的应用 |
| Application of energy spectrum CT perfusion imaging in distinguishing the severity of early cerebral infarction |
| 投稿时间：2022-09-23 修订日期：2023-03-15 |
| DOI：10.15972/j.cnki.43-1509/r.2023.04.020 |
| 中文关键词: 能谱CT灌注成像 早期脑梗死 病情程度 [ |
| 英文关键词:energy spectrum CT perfusion imaging early cerebral infarction severity |
| 基金项目:北京市属医院科研培育计划项目(PZ2018212) |
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| 中文摘要: |
| 目的探究能谱CT灌注成像在早期脑梗死病情程度鉴别中的应用价值。 方法回顾性选择拟诊脑梗死60例患者为脑梗死组,行CT平扫和CT灌注成像检测,另选同期50例健康个体为对照组。比较两组对称部位CT值差值(△Hu)。将脑梗死组分为Ⅰ期和Ⅱ期,比较不同分期患者能谱CT灌注成像参数、NIHSS得分、BI指数差异。分析能谱CT灌注成像参数与神经功能指标相关性。 结果脑梗死组CT平扫△Hu高于1.50 Hu者比例明显高于对照组(P＜0.05)。脑梗死组能谱CT灌注病灶检出率明显高于CT平扫；脑梗死组病灶中心、病灶周边、对侧区的相对达峰时间(rTTP)依次降低,相对脑血流量(rCBF)及相对脑血容量(rCBV)依次升高(P＜0.05)。脑梗死Ⅱ期组rTTP、NIHSS评分高于Ⅰ期组,rCBF、rCBV、BI指数低于Ⅰ期组(P＜0.05)。脑梗死患者NIHSS评分与rTTP呈正相关,与rCBF呈负相关,与rCBV呈负相关；BI指数与rTTP呈负相关(P＜0.05)。 结论能谱CT灌注成像对早期脑梗死病情程度具有较好诊断价值。 |
| 英文摘要: |
| AimTo explore the application value of spectral CT perfusion imaging in distinguishing the severity of early cerebral infarction. Methods60 patients with suspected cerebral infarction were retrospectively selected as the cerebral infarction group. CT plain scan and CT perfusion imaging were performed, 50 healthy individuals were selected as the control group during the same period. The difference of CT values (△Hu) in symmetric sites between the two groups was compared. The cerebral infarction group was divided into stage Ⅰ and stage Ⅱ, and the differences of energy spectrum CT perfusion imaging parameters, NIHSS scale score and Barthel (BI) index were compared. The correlation between energy spectrum CT perfusion imaging parameters and neural function indexes was analyzed. ResultsThe proportion of △Hu higher than 1.50 Hu in plain CT scan of cerebral infarction group was significantly higher than that in control group (P＜0.05). The detection rate of energy spectrum CT perfusion lesions in the cerebral infarction group was significantly higher than that of CT plain scan; The relative peak time (rTTP) of the center, periphery, and contralateral area of the cerebral infarction group were decreased sequentially, while the cerebral blood flow (rCBF) and relative cerebral blood volume (rCBV) were increased sequentially (P＜0.05). The rTTP and NIHSS scores in the stage Ⅱ group of cerebral infarction were higher than those in the stage Ⅰ group, while the rCBF, rCBV, and BI indices were lower than those in the stage Ⅰ group (P＜0.05). The NIHSS score of patients with cerebral infarction is positively correlated with rTTP, and negatively correlated with rCBF and rCBV; BI index is negatively correlated with rTTP (P＜0.05). ConclusionNergy spectrum CT perfusion imaging has good diagnostic value for the severity of early cerebral infarction. |
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