| 江帆,刘宁,翟鑫,管频,冯光球,陈娟,曾敏.亚临床甲状腺功能减退症患者TSH与肾上腺皮质功能的关系.[J].中南医学科学杂志.,2023,(1):90-92. |
| 亚临床甲状腺功能减退症患者TSH与肾上腺皮质功能的关系 |
| Correlation analysis between TSH and adrenal cortex function in subclinical hypothyroidism |
| 投稿时间：2022-02-17 修订日期：2022-10-09 |
| DOI：10.15972/j.cnki.43-1509/r.2023.01.023 |
| 中文关键词: 亚临床甲状腺功能减退症 肾上腺皮质功能 促甲状腺激素 促肾上腺皮质激素 皮质醇 [ |
| 英文关键词:subclinical hypothyroidism adrenal cortex function TSH ACTH CORT |
| 基金项目:海南省自然科学基金青年基金项目(819QN353)；海南省重点研发计划项目(ZDYF2020118)；海南医学院校级教育科研立项课题(HYYB202060)；海南省卫生健康行业科研项目(20A200430) |
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| 中文摘要: |
| 目的分析亚临床甲状腺功能减退症患者促甲状腺激素(TSH)与肾上腺皮质功能的关系。 方法选取150例亚临床甲状腺功能减退症患者为研究组,甲状腺功能正常的健康人群150例为对照组。比较两组TSH、游离三碘甲腺原氨酸(FT3)、游离甲状腺素(FT4)、皮质醇(CORT)和促肾上腺皮质激素(ACTH)水平。采用Pearson法分析亚临床甲状腺功能减退症患者TSH水平与ACTH、CORT水平的相关性。 结果与对照组比较,研究组患者TSH、ACTH水平升高,CORT水平降低(P＜0.05)。Pearson分析结果显示,亚临床甲状腺功能减退症患者TSH水平与ACTH水平呈正相关(P＜0.05),与CORT水平呈负相关(P＜0.05)。 结论亚临床甲状腺功能减退症患者血清TSH水平与肾上腺皮质功能指标ACTH、CORT水平存在相关性。 |
| 英文摘要: |
| AimTo explore the relationship between subclinical hypothyroidism thyroid-stimulating hormone (TSH) and adrenal cortex function. Methods150 patients with subclinical hypothyroidism were selected as the study group, and 150 healthy people with normal thyroid function were selected as the control group. The levels of TSH, free triiodothyronine (FT3), TSH, free thyroxine (FT4), cortisol (CORT), adrenocorticotropic hormone (ACTH) were compared between the two groups. Pearson method was used to analyze the correlation between TSH expression level and ACTH and CORT expression levels in patients with subclinical hypothyroidism. ResultsCompared with the control group, the TSH and ACTH levels in the study group were significantly higher, and the CORT level was significantly lower (P＜0.05). Pearson analysis showed that the TSH expression level in patients with subclinical hypothyroidism was positively correlated with the ACTH expression level (P＜0.05), and negatively correlated with the CORT expression level (P＜0.05). ConclusionSerum TSH level in patients with subclinical hypothyroidism is related to ACTH and CORT, and they may be involved in the occurrence and development of the disease. |
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