文育恒,谭小琴,朱帅,龚憬,刘小蝶,刘侃,叶明佶,张慧妮,谢宇.乳头状肾细胞癌患者的预后影响因素分析.[J].中南医学科学杂志.,2022,(4):551-553, 575.
乳头状肾细胞癌患者的预后影响因素分析
Prognostic influence factor analysis of papillary renal cell carcinoma
投稿时间:2021-11-02  修订日期:2022-03-03
DOI:10.15972/j.cnki.43-1509/r.2022.04.021
中文关键词:  乳头状肾细胞癌  预后  影响因素  HALP评分
英文关键词:papillary renal cell carcinoma  prognosis  influencing factor  HALP score
基金项目:湖南省科技厅项目(2020SK4006) 作者简介:文育恒,硕士研究生,研究方向为膀胱癌肿瘤标志物及预后相关研究,E-mail为15872695197@163.com。通信作者谢宇,博士,主任医师,研究方向为3D打印技术及手术机器人辅助手术治疗泌尿系肿瘤的应用研究,E-mail为xieyu420@sina.com。
作者单位E-mail
文育恒 南华大学衡阳医学院 湖南省肿瘤医院协作培养基地,湖南省衡阳市421001 e-mail为15872695197@163.com,e-mail为xieyu420@sina.com 
谭小琴 中山大学附属第一医院CCU科, 广东省广州市510000  
朱帅 湖南省肿瘤医院泌尿外科,湖南省长沙市410006  
龚憬 湖南省肿瘤医院泌尿外科,湖南省长沙市410006  
刘小蝶 湖南省肿瘤医院泌尿外科,湖南省长沙市410006  
刘侃 湖南省肿瘤医院泌尿外科,湖南省长沙市410006  
叶明佶 湖南省肿瘤医院泌尿外科,湖南省长沙市410006  
张慧妮 湖南省肿瘤医院泌尿外科,湖南省长沙市410006  
谢宇 湖南省肿瘤医院泌尿外科,湖南省长沙市410006 e-mail为15872695197@163.com,e-mail为xieyu420@sina.com 
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中文摘要:
      目的探讨乳头状肾细胞癌的预后影响因素。方法回顾性分析接受手术治疗的62例原发性乳头状肾细胞癌患者的临床资料,采用卡方检验分析临床资料与患者生存状态的相关性,并采用Kaplan-Meier生存曲线分析临床病理特征与患者总生存的关系。结果62例患者术后随访4~76个月,中位随访35个月,死亡8例。单因素分析结果显示,年龄、TNM分期、美国癌症联合委员会(AJCC)分期(第8版)、血红蛋白、白蛋白、淋巴细胞和血小板综合评分(HALP)是乳头状肾细胞癌患者预后的危险因素。高HALP组总生存率高于低HALP组(P<0.05)。结论年龄、TNM分期、HALP评分是乳头状肾细胞癌预后的影响因素。
英文摘要:
      To analyze the prognostic influence factors of papillary renal cell carcinoma(pRCC). MethodsThe clinical data of 62 patients with primary papillary renal cell carcinoma who underwent surgical treatment were retrospectively analyzed, and the correlation between clinical data and patient survival status was analyzed using the chi-square test, and the relationship between clinicopathological characteristics and overall patient survival was analyzed using the Kaplan-Meier survival curve. Results62 patients with pRCC were followed up for 4 to 76 months after surgery, with a median follow-up of 35 months, 8 died. The results of the univariate analysis showed that age, TNM stage, the eighth edition of the American joint committee on cancer (AJCC) staging system, combined hemoglobin, albumin, lymphocyte, and platelet score (HALP) were risk factors for the prognosis of pRCC. The overall survival rates were higher in the high HALP than in the low HALP(P<0.05). ConclusionAge, TNM stage, HALP score was prognostic influence factors for pRCC.
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