| 全强,黄冬花,陈秋月,邓书敏,蔡淑芬.不同类型心力衰竭患者超声心动图参数、NT-proBNP及其临床意义.[J].中南医学科学杂志.,2022,(3):449-451, 465. |
| 不同类型心力衰竭患者超声心动图参数、NT-proBNP及其临床意义 |
| Ultrasound cardiogram index, NT-proBNP level and clinical significance in patients with different types of heart failure |
| 投稿时间：2021-01-13 修订日期：2021-09-20 |
| DOI：10.15972/j.cnki.43-1509/r.2022.03.036 |
| 中文关键词: 超声心动图 N-末端脑钠肽前体 心力衰竭 射血分数 心功能分级 |
| 英文关键词:ultrasound cardiogram N-terminal pro brain natriuretic peptide heart failure ejection fraction cardiac function grading |
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| 中文摘要: |
| 目的探讨不同类型心力衰竭患者超声心动图参数、血浆N-末端脑钠肽前体(NT-proBNP)水平及其临床意义。方法选取心力衰竭患者98例根据超声心动图参数左心室射血分数(LVEF)水平分为LVEF减低型心力衰竭(HFREF)组、LVEF保留型心力衰竭(HFPEF)组和LVEF中间型心力衰竭(HFMEF)组。比较3组一般资料、血浆NT-proBNP水平和超声心动图参数左心室舒张期末内径(LVEDD)、左心房前后径(LAD)和LVEF,分析NT-proBNP水平与LVEDD、LAD、LVEF和心功能分级的相关性。结果HFREF组收缩压低于HFPEF组和HFMEF组,HFPEF组、HFMEF组和HFREF组血浆NT-proBNP和LVEDD依次增高,LVEF依次降低(P＜0.05)；HFMEF组和HFREF组LAD高于HFPEF组(P＜0.05)；3组心功能分级差异有显著性(P＜0.05)。各组NT-proBNP水平均与LVEDD、LAD和心功能分级呈正相关,与LVEF呈负相关(P＜0.05)。结论HFREF患者超声心动图参数与心功能分级明显相关,NT-proBNP水平比HFPEF和HFMEF患者明显更高,其对于早期判断患者心力衰竭类型和心功能具有一定指导价值。 |
| 英文摘要: |
| To explore the level and clinical significance of ultrasound cardiogram index, N-terminal pro brain natriuretic peptide (NT-proBNP) in patients with different types of heart failure. MethodsAccording to different left ventricular ejection fraction (LVEF), 98 patients with heart failure were divided into heart failure with reduced ejection fraction (HFREF) group, heart failure with preserved ejection fraction (HFPEF) group and heart failure with middle ejection fraction(HFMEF) group. The general data,level of plasma NT-proBNP,left ventricular end diastolic diameter (LVEDD), left atrium anterior and posterior diameter (LAD) and LVEF were compared among the three groups.The correlation between NT-proBNP level and LVEDD, LAD, LVEF,cardiac function grading was analyzed. ResultsThe systolic blood pressure in HFREF group was lower than that in HFPEF group and HFMEF group. In HFPEF group, HFMEF group and HFREF group,plasma NT-proBNP and LVEDD were increased, while LVEF was decreased sequentially(P＜0.05). LAD in HFMEF group and HFREF group was higher than that in HFPEF group (P＜0.05). There were significant differences in cardiac function grading among the three groups (P＜0.05). NT-proBNP level was positively correlated with LVEDD, LAD and cardiac functional grading (P＜0.05), while negatively correlated with LVEF (P＜0.05). ConclusionsThe level of plasma NT-proBNP in HFREF patients is significantly higher than that in HFPEF and HFMEF patients, which is significantly correlated with UCG parameters and cardiac function grading. It has certain guidance value in early determining the types of heart failure and cardiac function. |
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