| 杨晓德,蒋兰兰,谢晓竞.血红蛋白水平对2型糖尿病患者肌少症的影响.[J].中南医学科学杂志.,2022,(3):398-401. |
| 血红蛋白水平对2型糖尿病患者肌少症的影响 |
| Effect of hemoglobin level on sarcopenia in type 2 diabetic patients |
| 投稿时间：2021-10-01 修订日期：2022-02-12 |
| DOI：10.15972/j.cnki.43-1509/r.2022.03.022 |
| 中文关键词: 2型糖尿病 肌少症 血红蛋白 |
| 英文关键词:type 2 diabetes sarcopenia hemoglobin |
| 基金项目:南京市医学科技发展项目(YKK17107) 作者简介:杨晓德,硕士研究生,研究方向为糖尿病慢性并发症,E-mail为2281060963@qq.com。通信作者谢晓竞,硕士,主任医师,硕士研究生导师,研究方向为糖尿病慢性并发症,E-mail为xxjnanjing@sina.com。 |
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| 中文摘要: |
| 目的分析血红蛋白水平对2型糖尿病(T2DM)患者肌少症的影响。方法将864例T2DM患者根据肌少症诊断标准分为肌少症组154例与非肌少症组710例。比较两组患者一般临床资料及相关生化、血常规指标。将血红蛋白(Hb)水平按四分位法分组,比较不同Hb水平肌少症的患病率。Spearman分析Hb水平与握力、骨骼肌质量指数(SMI)的相关性。受试者工作特征曲线(ROC曲线)分析肌少症患者Hb最佳临界值。结果T2DM肌少症总患病率为17.8%,男性患病率为14.2%,女性患病率为23.7%。随着血红蛋白水平的升高,肌少症患病率逐渐降低。Spearman相关分析结果显示Hb与SMI、握力呈正相关(P＜0.001),ROC结果显示Hb的曲线下面积(AUC)为0.737。结论Hb水平的升高可降低2型糖尿病患者肌少症的患病率。 |
| 英文摘要: |
| To analyze the effect of hemoglobin level on sarcopenia in type 2 diabetes mellitus (T2DM) patients. MethodsAccording to the diagnostic criteria of sarcopenia, 864 T2DM patients were divided into sarcopenia group (154 cases) and non-sarcopenia group (710 cases). The general clinical data and related biochemical and blood routine examinations were compared between the two groups. Hemoglobin (Hb) levels were quartile grouped to compare the prevalence of sarcopenia. Spearman was used to analyze the correlation between Hb level and grip strength and SMI. Receiver operating characteristic curve (ROC curve) was used to analyze the optimal cut-off value of Hb in patients with sarcopenia. ResultsThe overall prevalence of T2DM sarcopenia was 17.8%, 14.2% in males and 23.7% in females. As hemoglobin levels increases, sarcopenia decrease. Spearman correlation analysis showed that Hb was positively correlated with SMI and grip strength (P＜0.001), ROC results showed that the area under curve (AUC) of Hb was 0.737. ConclusionIncreased hemoglobin levels can reduce the risk of sarcopenia in patients with type 2 diabetes. |
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