宁旦,胡少飞,马聆桦,劳诚毅,朱茂灵.腹腔镜下输卵管妊娠物清除联合近端阻断术对输卵管妊娠患者妊娠结局的影响.[J].中南医学科学杂志.,2022,(3):381-383, 387.
腹腔镜下输卵管妊娠物清除联合近端阻断术对输卵管妊娠患者妊娠结局的影响
Effect of laparoscopic tubal pregnancy removal combined with proximal block on pregnancy outcome of tubal pregnancy patients
投稿时间:2021-08-06  修订日期:2022-02-28
DOI:10.15972/j.cnki.43-1509/r.2022.03.017
中文关键词:  腹腔镜  输卵管妊娠物清除  近端阻断术  输卵管妊娠  妊娠结局
英文关键词:laparoscope  pregnancy clearance  proximal end occlusion  tubal pregnancy  pregnancy outcome
基金项目:广西壮族自治区卫生和计划生育委员会科研课题(Z20180245) 作者简介:宁旦,副主任医师,研究方向为妇女生殖与健康,E-mail为ningdan2536547388@126.com。通信作者朱茂灵,主任医师,研究方向为妇幼保健管理,E-mail为3152284326@qq.com。
作者单位E-mail
宁旦 妇产科, e-mail为ningdan2536547388@126.com,e-mail为3152284326@qq.com 
胡少飞 妇产科,  
马聆桦 检验科,  
劳诚毅 麻醉科,广西省南宁市 530011  
朱茂灵 妇产科, e-mail为ningdan2536547388@126.com,e-mail为3152284326@qq.com 
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中文摘要:
      目的观察腹腔镜下输卵管妊娠物清除联合近端阻断术对输卵管妊娠患者妊娠结局的影响。方法110例输卵管妊娠患者根据手术方式均分为联合手术组与保守手术组。联合手术组为腹腔镜下输卵管妊娠物清除联合近端阻断术,保守手术组为腹腔镜下输卵管保守手术。比较两组患者手术及术后恢复相关指标、术后3个月卵巢储备功能指标及术后1年内再次妊娠结局。结果两组患者手术与术后恢复相关指标、术后3天血清β-绒毛膜促性腺激素(β-HCG)下降率及术后3个月卵巢窦卵泡数、卵巢截面积、卵巢动脉阻力指数均无统计学意义(P>0.05)。术后1年内,联合手术组宫内妊娠率高于保守手术组(P<0.05),异位妊娠及未受孕率低于保守手术组(P<0.05);联合手术组宫内妊娠患者不良妊娠结局发生率低于保守手术组(P<0.05)。结论腹腔镜下输卵管妊娠物清除联合近端阻断术对输卵管妊娠患者血清β-HCG及卵巢储备功能无不良影响,且有利于改善再次妊娠结局。
英文摘要:
      To observe the effect of laparoscopic tubal pregnancy removal combined with proximal block on pregnancy outcome of tubal pregnancy. MethodsAccording to the surgical methods, 110 patients with tubal pregnancy were divided into combined operation group and conservative operation group. Laparoscopic tubal pregnancy removal combined with proximal block was used in the combined operation group, laparoscopic tubal conservative surgery was used in the conservative operation group. The indexes related to surgery and postoperative recovery, ovarian reserve function indexes 3 months after surgery and repregnancy outcomes within 1 year after surgery were compared between the two groups.ResultsThere were no significant differences in the related indicators of operation and postoperative recovery, the decrease rate of serum β -chorionic gonadotropin (β-HCG) 3 days after surgery, number of ovarian sinus follicles, cross-sectional area of ovary and ovarian artery resistance index 3 months after surgery between 2 groups(P>0.05). The intrauterine pregnancy rate in the combined operation group was higher than that in the conservative operation group (P<0.05), the rate of ectopic pregnancy and non-conception was lower than that of conservative surgery group (P<0.05), the incidence of adverse pregnancy outcome in combined operation group was lower than that in conservative operation group (P<0.05). ConclusionLaparoscopic tubal pregnancy removal combined with proximal block had no adverse effects on serum β-HCG and ovarian reserve function of tubal pregnancy patients, and was beneficial to improving the outcome of second pregnancy.
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