王磊,高景宇,尹海军,魏洪亮,张爱民.经输尿管镜钬激光碎石术与Cyberwand超声碎石术治疗输尿管结石的疗效对比.[J].中南医学科学杂志.,2022,(3):370-372.
经输尿管镜钬激光碎石术与Cyberwand超声碎石术治疗输尿管结石的疗效对比
Comparative study on curative effect of ureteroscopic holmium laser lithotripsy and Cyberwand ultrasonic lithotripsy on ureteral calculi
投稿时间:2021-06-23  修订日期:2021-09-10
DOI:10.15972/j.cnki.43-1509/r.2022.03.014
中文关键词:  输尿管结石  输尿管镜钬激光碎石术  Cyberwand超声碎石术  应激反应  肾功能
英文关键词:ureteral calculi  ureteroscopic holmium laser lithotripsy  Cyberwand ultrasonic lithotripsy  stress response  renal function
基金项目:河北省重点研发计划项目(162777220) 作者简介:王磊,硕士,副主任医师,研究方向为泌尿系肿瘤和结石,E-mail为wlei99@163.com。通信作者高景宇,硕士,副主任医师,研究方向为微创治疗泌尿系结石,E-mail为lutumanman@sina.com。
作者单位E-mail
王磊 河北医科大学第一医院泌尿外科,河北省石家庄市 050000 e-mail为wlei99@163.com,e-mail为lutumanman@sina.com 
高景宇 河北医科大学第一医院泌尿外科,河北省石家庄市 050000 e-mail为wlei99@163.com,e-mail为lutumanman@sina.com 
尹海军 河北医科大学第一医院泌尿外科,河北省石家庄市 050000  
魏洪亮 河北医科大学第一医院泌尿外科,河北省石家庄市 050000  
张爱民 河北医科大学第一医院泌尿外科,河北省石家庄市 050000  
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中文摘要:
      目的比较经输尿管镜钬激光碎石术与Cyberwand超声碎石术治疗输尿管结石的疗效。方法输尿管结石患者80例,随机分为对照组和试验组各40例,对照组采用Cyberwand超声碎石术,试验组采用经输尿管镜钬激光碎石术,比较两组患者围手术期指标、肾功能指标、血清应激反应指标水平、术后结石残留率及并发症发生率。结果试验组患者的手术时间、术中出血量、住院时间均低于对照组(P<0.05);两组术后血尿素氮(BUN)、肌酐(Cr)、白细胞计数(WBC)、中性粒细胞计数(NEUT)、皮质醇(Cor)、肾上腺素(EP)水平及并发症发生率差异无显著性(P>0.05);试验组术后结石残留率低于对照组(P<0.05)。结论两种手术方式对输尿管结石患者肾功能指标、血清氧化应激指标的影响较小,经输尿管镜钬激光碎石术可显著降低患者手术时间、术中出血量、住院时间及术后结石残留率。
英文摘要:
      To compare the efficacy of ureteroscopic holmium laser lithotripsy and Cyberwand ultrasonic lithotripsy on ureteral calculi. MethodsEighty patients with ureteral calculi were enrolled. They were divided into control group and experimental group with 40 cases in each group. The control group underwent Cyberwand ultrasonic lithotripsy, while experimental group underwent ureteroscopic holmium laser lithotripsy. The perioperative indexes, renal function indexes, levels of serum stress response indexes, postoperative stone residual rate and incidence of complications were compared between the two groups. ResultsAfter surgery, operation time, intraoperative blood loss and hospitalization time in experimental group were lower than those in control group (P<0.05). After surgery, there were no significant differences in levels of blood urea nitrogen (BUN) and creatinine (Cr), white blood cell count (WBC), neutrophil count (NEUT), cortisol (Cor) and epinephrine (EP) and complication rate between the two groups (P>0.05). The postoperative stone residual rate in experimental group was lower than that in control group (P<0.05). ConclusionsThe effects of the two surgical methods are few on renal function and serum oxidative stress indexes in patients with ureteral calculi. Compared with Cyberwand ultrasound lithotripsy, ureteroscopic holmium laser lithotripsy can significantly reduce operation time, intraoperative blood loss, hospitalization time and stone residual rate.
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