| 马觉,蒋庆庆,谢优优,袁君,丁嘉佩.膀胱充盈体积对宫颈癌三维近距离放疗剂量分布的影响.[J].中南医学科学杂志.,2021,(5):591-594. |
| 膀胱充盈体积对宫颈癌三维近距离放疗剂量分布的影响 |
| Effect of bladder filling volume on dose distribution of three-dimensional brachytherapy for cervical cancer |
| 投稿时间：2021-02-05 修订日期：2021-05-08 |
| DOI：10.15972/j.cnki.43-1509/r.2021.05.023 |
| 中文关键词: 宫颈癌 三维近距离放射治疗 膀胱充盈体积 剂量分布 |
| 英文关键词:cervical cancer three-dimensional intracavitary afterloading brachytherapy bladder filling volume dose distribution |
| 基金项目:台州市第一批社会发展科技计划项目(20ywa04) 作者简介:马觉,硕士研究生,住院医师,研究方向为妇科肿瘤的放化疗,E-mail为547298968@qq.com。通信作者丁嘉佩,硕士研究生,主治医师,研究方向为妇科肿瘤的放化疗,E-mail为1017586086@qq.com。 |
|
| 摘要点击次数: 333 |
| 全文下载次数: 668 |
| 中文摘要: |
| 目的分析膀胱充盈体积对CT引导的未手术宫颈癌三维近距离放射治疗(3D-ICABT)计划中靶区及危及器官(OARs)剂量分布的影响以探寻最佳膀胱充盈体积。方法选取37例未手术的宫颈癌患者,共121次CT引导的近距离放射治疗(ICBT),按膀胱充盈体积大小顺序分为＜80 mL组、80～160 mL组、160～240 mL组、≥240 mL组。比较各组临床靶区及OARs的剂量。结果各组膀胱、小肠的0.1 cm3、1 cm3、2 cm3体积接受的最小剂量(D0.1cc、D1cc、D2cc)差异具有统计学意义(P＜0.05),＜80 mL组膀胱所照射的剂量最低,小肠的受量最高,但在安全剂量范围。各组临床靶区、直肠、乙状结肠的D0.1cc、D1cc、D2cc剂量差异无统计学意义(P＞0.05),＜80 mL组直肠、乙状结肠所照射的剂量最低。结论临床靶区、直肠、乙状结肠的剂量受膀胱充盈体积的影响较小,而膀胱、小肠的剂量因膀胱充盈体积的变化显著；CT引导的未手术宫颈癌的3D-ICABT时膀胱充盈体积＜80 mL为最佳充盈体积。 |
| 英文摘要: |
| To analyze the effect of different volume of bladder on the dose distribution of target and organs at risk(OARs) in CT guided three-dimensional intracavitary afterloading brachytherapy for non-surgical cervical cancer and to explore the best bladder filling volume. Methods37 patients with non-surgical cervical cancer were selected and there were a total of 121 CT guided intracayitary brachytherapy. And they were divided into 4 groups according to the volume of the bladder:group ＜80 mL, group 80-160 mL, group 160-240 mL, group ≥240 mL. Doses of clinical target and OARs of each group were compared. ResultsThe D0.1cc, D1cc and D2cc of the bladder and small intestine of each group were statistically significant different(P＜0.05),and the bladder dose in group ＜80 mL was the lowest. The small intestine dose in group ＜80 mL was highest, still within the safe dose range. Each group of the clinical target, the D0.1cc, D1cc, and D2cc of the rectum and sigmoid colon were not statistically different (P＞0.05), and the doses of rectum and sigmoid colon in group ＜80 mL were the lowest. ConclusionsDifferent bladder volume had little effect on the dose of the clinical target, the rectum and sigmoid colon,but it had significant effect on the dose of the bladder and small intestine.Less than 80 mL bladder filling volume was the best when non-surgical cervical cancer patients were treated with three-dimensional brachytherapy. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
| 关闭 |
|
|
|