| 许春香,李晔,蒋建中.老年2型糖尿病肾病血液透析期间肺部感染的危险因素分析.[J].中南医学科学杂志.,2021,(5):536-539. |
| 老年2型糖尿病肾病血液透析期间肺部感染的危险因素分析 |
| Risk factors of pulmonary infection during hemodialysis in elderly patients with type 2 diabetic nephropathy |
| 投稿时间：2020-08-24 修订日期：2020-12-07 |
| DOI：10.15972/j.cnki.43-1509/r.2021.05.009 |
| 中文关键词: 老年 2型糖尿病 血液透析 肺部感染 |
| 英文关键词:elderly type 2 diabetes hemodialysis pulmonary infection |
| 基金项目:江苏省自然科学基金青年基金项目(BK20170359) 作者简介:许春香,主治医师,研究方向为老年肾脏医学,E-mail为yufangcang19840116@163.com。通信作者蒋建中,主任医师,研究方向为老年医学,E-mail为yufangcang19840116@163.com。 |
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| 中文摘要: |
| 目的观察老年2型糖尿病肾病患者血液透析期间肺部感染的危险因素。方法选取81例年龄＞60岁的规律维持性血液透析2型糖尿病肾病患者进行观察,并对患者进行随访,观察患者肺部感染情况并分析影响因素。结果随访时间6～24月,共11例患者发生肺部感染,发生率为13.6%,其共感染22种病原菌,革兰阴性菌感染最高(68.2%)。肺部感染组患者年龄>80岁、糖尿病病程＞10年、高血压、白蛋白≤35 g/L、总蛋白≤60 g/L、容量负荷、服用促胃动力药物、糖化血红蛋白＞7%比例均高于无肺部感染组(P＜0.05)。Logistic回归分析结果显示,年龄、容量负荷、使用促胃动力药物、糖化血红蛋白、白蛋白是老年糖尿病肾病血液透析期间肺部感染的独立影响因素(P＜0.05)。结论年龄＞80岁、容量负荷、使用促胃动力药物、高糖化血红蛋白、低白蛋白是老年2型糖尿病肾病患者在血液透析期间发生肺部感染的危险因素。 |
| 英文摘要: |
| To observe the risk factors of pulmonary infection during hemodialysis in elderly patients with diabetic nephropathy. MethodsA total of 81 patients ＞60 years old with type 2 diabetic nephropathy who underwent regular maintenance hemodialysis were selected. The patients were followed up to observe the status of lung infection and analyze the influencing factors. ResultsThe follow-up time ranged from 6 months to 24 months. A total of 11 patients developed pulmonary infections, with an incidence rate of 13.6%. 11 patients with pulmonary infection were infected with 22 types of bacteria, among which Gram-negative bacteria infection was the highest (68.2%). In the lung infection group, the proportion of patients with age ＞80 years, diabetes ＞10 years,hypertension, albumin ≤35 h/L, total protein ≤60 g/L, volume load, taking prokinetic drugs, glycosylated hemoglobin ＞7%, were higher than that of the group without lung infection (P＜0.05). Logistic regression analysis showed that age, volume load, use of prokinetic drugs, and glycated hemoglobin, albumin were independent influencing factors of hemodialysis-related pulmonary infection in elderly diabetic nephropathy (P＜0.05). ConclusionElderly diabetic nephropathy patients with age ＞80 years old, volume load, gastric motility drugs, and high glycated hemoglobin, low albumin are risk factors for pulmonary infection during hemodialysis in elderly patients with type 2 diabetic nephropathy. |
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