| 田丽槟,徐嘉蔚,陈莉莉,明小琼,房莹.MDT模式的营养干预对妊娠期糖尿病糖脂代谢、妊娠结局及新生儿免疫功能的影响.[J].中南医学科学杂志.,2021,(2):207-212. |
| MDT模式的营养干预对妊娠期糖尿病糖脂代谢、妊娠结局及新生儿免疫功能的影响 |
| Effects of nutrition intervention based on MDT on glucose and lipid metabolism, pregnancy outcome and neonatal immune function in pregnant women with gestational diabetes mellitus |
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| DOI：10.15972/j.cnki.43-1509/r.2021.02.018 |
| 中文关键词: 多学科团队协作模式 营养干预 妊娠期糖尿病 糖脂代谢 妊娠结局 免疫功能 [ |
| 英文关键词:multi-disciplinary team nutritional intervention gestational diabetes mellitus glucose and lipid metabolism pregnancy outcome immune function |
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| 中文摘要: |
| 目的探讨基于多学科团队协作(MDT)模式的营养干预对妊娠期糖尿病(GDM)孕妇糖脂代谢、妊娠结局及新生儿免疫功能的影响。方法选取规范产检并分娩的GDM孕妇150例,采用随机数字表法将其分为对照组及观察组,每组各75例。对照组给予常规营养干预,观察组给予基于MDT模式的营养干预。对比两组GDM孕妇糖脂代谢指标、妊娠结局及新生儿免疫功能。结果观察组孕妇干预后空腹血糖(FBG)、餐后2h血糖(2hPBG)、糖化血红蛋白(HbA1c)、稳态模型-胰岛素抵抗指数(HOMA-IR)及甘油三酯(TG)低于对照组(P＜0.05)；观察组孕妇顺产率高于对照组(P＜0.05)；观察组孕妇剖宫产率、妊娠期高血压、新生儿低血糖、巨大儿发生率低于对照组(P＜0.05)；观察组新生儿外周血免疫球蛋白G(IgG)水平高于对照组(P＜0.05)；观察组新生儿CD3+、CD4+、CD8+及CD4+/CD8+低于对照组(P＜0.05)。结论基于MDT模式的营养干预可有效调控GDM孕妇糖脂代谢,提升新生儿免疫功能,改善妊娠结局。 |
| 英文摘要: |
| To investigate the effect of nutrition intervention based on multi-disciplinary team (MDT) on glucose and lipid metabolism, pregnancy outcome and neonatal immune function in pregnant women with gestational diabetes mellitus (GDM). MethodsOne hundred and fifty cases of GDM pregnant women who underwent standardized prenatal examination and delivery in China Resources WISCO General Hospital were selected and they were randomly divided into control group and observation group, with 75 cases in each group. The control group was given conventional nutritional intervention, and the observation group was given nutritional intervention based on MDT. The glucose and lipid metabolism indexes, pregnancy outcome and neonatal immune function of GDM pregnant women were compared between the two groups. ResultsFasting blood glucose (FBG), 2-hour postprandial blood glucose (2hPBG), glycosylated hemoglobin (HbA1c), homeostasis model insulin resistance index (HOMA-IR) and triglyceride (TG) in the observation group were lower than those in the control group (P＜0.05); The rate of natural birth section in the observation group was higher than that in the control group (P＜0.05), The cesarean section, pregnancy induced hypertension, neonatal hypoglycemia and macrosomia in the observation group were lower than those in the control group (P＜0.05); the level of peripheral blood immunoglobulin G (IgG) in the observation group was higher than that in the control group (P＜0.05); CD3+, CD4+, CD8+ and CD4+/CD8+ in the observation group were lower than those in the control group (P＜0.05). ConclusionNutritional intervention based on MDT can effectively regulate glucose and lipid metabolism of GDM pregnant women, improve neonatal immune function and improve pregnancy outcome. |
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