| 吴鹏,陶婷,王向东,孙中平,王佐,吴仕元.孕早中期胎盘生长因子水平对高危孕妇妊娠结局预测价值.[J].中南医学科学杂志.,2020,(5):513-515. |
| 孕早中期胎盘生长因子水平对高危孕妇妊娠结局预测价值 |
| Prediction value of placental growth factor level in early and middle pregnancy for pregnancy outcomes in high-risk pregnant women |
| 投稿时间：2020-07-01 修订日期：2020-08-28 |
| DOI：10.15972/j.cnki.43-1509/r.2020.05.017 |
| 中文关键词: 胎盘生长因子 高危因素 妊娠结局 |
| 英文关键词:placental growth factor high risk factors adverse pregnancy outcome |
| 基金项目: |
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| 中文摘要: |
| 为探讨孕早中期胎盘生长因子(PLGF)对高危孕妇妊娠结局的预测价值,选取在本院产检且妊娠12~15周PLGF水平异常产妇169例为研究对象(研究组),随机抽取同期内在本院产检PLGF水平正常的相同孕周产妇117例作为对照(对照组),比较两组产妇妊娠的高危因素及妊娠结局。结果显示,与对照组比较,研究组妊娠高危因素(体重指数≥24、年龄≥35岁、辅助生殖技术受孕)的比例显著增高,且妊娠期糖尿病、子痫前期、早期早产等不良妊娠发生率显著增高(P＜0.05)。结果表明,孕早、中期PLGF水平异常对高危妊娠妇女不良妊娠结局有预测价值。 |
| 英文摘要: |
| To investigate the predictive value of placental growth factor(PLGF) in early and middle pregnancy for pregnancy outcomes in high-risk pregnant women. 169 women with abnormal PLGF during the period of 12-15 weeks of gestation were served as the research subjects (study group). 117 women at the same gestation with normal PLGF were served as control (control group). The high risk factors for pregnancy and adverse pregnancy outcomes were compared between the two groups. The results showed, compared to the control group, the study group has higher risk factors for pregnancy (body mass index≥24, age≥35 years, assisted reproductive technology pregnancy) and higher adverse pregnancy rates such as gestational diabetes (GDM), preeclampsia, preterm birth (P＜0.05). The PLGF level in the first and second trimester of pregnancy has a predictive value for adverse pregnancy outcomes in high-risk pregnant women. |
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