| 刘艳,曾高峰.骨标志物水平与2型糖尿病患者心血管疾病风险研究.[J].中南医学科学杂志.,2020,(4):356-359. |
| 骨标志物水平与2型糖尿病患者心血管疾病风险研究 |
| Study of the bone markers and the risk of cardiovascular disease in patients with type 2 diabetes mellitus |
| 投稿时间：2020-03-16 修订日期：2020-06-03 |
| DOI：10.15972/j.cnki.43-1509/r.2020.04.005 |
| 中文关键词: 骨标志物 心血管疾病 糖尿病 相关性 |
| 英文关键词:bone markers cardiovascular disease diabetes correlation |
| 基金项目: |
|
| 摘要点击次数: 701 |
| 全文下载次数: 699 |
| 中文摘要: |
| 为探讨2型糖尿病患者中6种骨标志物水平与患心血管疾病(CVD)风险的相关性,将200例2型糖尿病患者按有无CVD,分为无CVD患者(n=100)和CVD患者(n=100),采用多重试剂盒检测血中6种骨标记物,Cox多因素分析评估2型糖尿病骨标志物与CVD风险的关联性。结果显示,骨桥蛋白增高与患CVD风险呈正相关,其他骨标志物与CVD风险无相关性。骨桥蛋白是2型糖尿病患者发生心血管疾病风险的重要相关因素。 |
| 英文摘要: |
| To investigate the relationship between levels of 6 bone markers and the risk of cardiovascular disease (CVD) in patients with type 2 diabetic mellitus, 200 patients with type 2 diabetes were divided into CVD Free patients (n=100) and CVD patients (n=100). The proteins of 6 bone markers were analyzed by multiple kits, Cox multivariate analysis was used to assess the association between the risk of CVD and the bone markers of type 2 diabetes. The results showed that the increase of osteopontin was related to the increase of CVD risk, and other bone markers were not related to susceptibility of CVD. In conclusion, osteopontin is an important risk factor for cardiovascular disease in patients with type 2 diabetes. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
| 关闭 |