王化湘,彭辉灿.眼底激光联合康柏西普治疗糖尿病视网膜病变的临床效果观察.[J].中南医学科学杂志.,2019,(6):640-642, 672.
眼底激光联合康柏西普治疗糖尿病视网膜病变的临床效果观察
Observation of clinical effect of fundus laser combined with compaccip in treating DR
投稿时间:2019-08-15  修订日期:2019-10-24
DOI:10.15972/j.cnki.43-1509/r.2019.06.020
中文关键词:  眼底激光  康柏西普  糖尿病视网膜病变  血流动力学  炎症因子  氧化应激反应
英文关键词:fundus laser  compaccip  diabetic retinopathy  hemodynamics  inflammatory cytokines  oxidative stress response
基金项目:
作者单位
王化湘 南华大学附属第二医院眼科,湖南 衡阳 421001
湖南省隆回县人民医院,湖南 邵阳 422200 
彭辉灿 南华大学附属第二医院眼科,湖南 衡阳 421001 
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中文摘要:
      眼底激光是治疗糖尿病视网膜病变的主要方式,但是激光治疗后部分患者视力恢复情况并不理想。康柏西普眼用注射液能够抑制血管的新生,改善患者的微炎症水平,增强抗氧化能力。本研究为分析眼底激光联合康柏西普治疗糖尿病视网膜病变(DR)的效果,选取200例DR患者作为研究对象,运用对比实验的方法进行研究。结果显示,两种治疗措施联用,可降低患者视力的LogMAR值,且能明显改善患者的血流动力学、氧化应激以及炎症因子的水平,并对此进行统计学分析。所以,运用眼底激光联合康柏西普的疗法治疗DR,能明显改善患者的病情,可在临床上广泛运用。
英文摘要:
      Fundus laser is the main way to treat diabetic retinopathy, but the recovery of vision in some patients after laser treatment is not ideal. Compaqip Ophthalmic Injection can inhibit the regeneration of blood vessels, improve the level of microinflammation in patients, and enhance antioxidant capacity. This study was to analyze the effect of fundus laser combined with Composcide in the treatment of diabetic retinopathy (DR). 200 patients with diabetic retinopathy were selected as the research object, and the comparative experimental method was used to study. The combination of the two treatments can reduce the LogMAR value of the patient's vision, and can significantly improve the patient's hemodynamics, oxidative stress and inflammatory factors. Therefore, this study believes that the use of fundus laser combined with Composcipal therapy for DR can significantly improve the patient's condition and can be widely used in clinical practice.
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