| 斯洁骊,罗怡,李京晶.联合检测评估糖尿病合并甲亢患者病情进展的价值.[J].中南医学科学杂志.,2019,(4):411-413. |
| 联合检测评估糖尿病合并甲亢患者病情进展的价值 |
| Value of combined detection in evaluating the progress of diabetes mellitus with hyperthyroidism |
| 投稿时间：2019-01-14 修订日期：2019-03-05 |
| DOI：10.15972/j.cnki.43-1509/r.2019.04.019 |
| 中文关键词: 糖尿病 甲状腺功能亢进 甲状旁腺激素 甲状腺过氧化物酶抗体 谷氨酸脱羧酶抗体 |
| 英文关键词:diabetes hyperthyroidism parathyroid hormone thyroid peroxidase antibody glutamate decarboxylase antibody |
| 基金项目: |
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| 中文摘要: |
| 为研究甲状旁腺激素(PTH)、甲状腺过氧化物酶抗体(TPOAb)、谷氨酸脱羧酶抗体(GADA)联合检测在糖尿病合并甲亢患者病情评估中的应用价值。选取95例糖尿病合并甲亢患者(观察组)和50例健康者(对照组),检测血浆中PTH、TPOAb、GADA水平,并绘制ROC曲线,以分析联合检测的灵敏度和特异度。结果显示, PTH、TPOAb、GADA联合检测的灵敏度、特异度均显著高于各指标单一检测(P<0.05),提示PTH、TPOAb和GADA三者联合检测有利于提高诊断的准确度,对较好预测有无甲亢发生具有重要意义。 |
| 英文摘要: |
| To study the application value of combined detection of PTH, TPOAb and GADA in the assessment of diabetic patients with hyperthyroidism. Ninety-five patients with diabetes mellitus complicated with hyperthyroidism (observation group) and 50 healthy persons (control group) were selected. The levels of PTH, TPOAb and GADA in plasma were measured, and ROC curves were drawn to analyze the sensitivity and specificity of the combined detection. The results showed that the sensitivity and specificity of combined detection of PTH, TPOAb and GADA were significantly higher than that of single detection of each index (P<0.05), suggesting that the combined detection of PTH, TPOAb and GADA is helpful to improve the accuracy of diagnosis and has important significance for effective evaluation of the disease and whether there was hyperthyroidism in diabetic patients. |
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