蒋召芹,张重阳,李广章,穆永芳,刘宇鹏,聂亚冬.探讨胰岛素强化治疗对急诊脑梗塞溶栓患者出血高危因素的影响分析.[J].中南医学科学杂志.,2019,(2):143-145, 172. |
探讨胰岛素强化治疗对急诊脑梗塞溶栓患者出血高危因素的影响分析 |
Effect of intensive insulin therapy on risk factors for bleeding in patients with acute cerebral infarction after thrombolytic therapy |
投稿时间:2018-09-19 修订日期:2018-11-28 |
DOI:10.15972/j.cnki.43-1509/r.2019.02.007 |
中文关键词: 胰岛素强化治疗 急诊脑梗塞 溶栓 高危因素 血糖 |
英文关键词:intensive insulin therapy emergency cerebral infarction thrombolysis risk factors blood sugar |
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中文摘要: |
为探讨胰岛素强化治疗对急诊脑梗塞溶栓患者高危因素的影响分析,将纳入患者分为常规治疗组50例和胰岛素强化治疗组50例,经治疗后,两组患者的血糖水平、NIHSS评分及mRS评分较治疗前均降低。与常规治疗组相比较,胰岛素强化治疗组的转化率低。与未出血组相比,发生出血转化的患者伴有血糖高、发病至静脉溶栓时间长、溶栓前NIHSS评分高、CT低密度病灶多。证实了胰岛素强化治疗可以降低溶栓后出血转化率,改善预后。 |
英文摘要: |
In order to investigate the effect of intensive insulin therapy on the high risk factors of thrombolytic patients with acute cerebral infarction, the patients were divided into routine treatment group (n=50) and insulin intensive therapy group (n=50). The blood glucose level of the two groups was significantly lower than that before treatment. Compared with the conventional treatment group, the conversion rate of insulin intensive treatment group was lower. Compared with the non-bleeding group, the patients with hemorrhage and transformation were accompanied with high blood glucose, long time to intravenous thrombolysis, and high nihss score before thrombolytic therapy. It is confirmed that intensive insulin therapy can reduce the conversion rate of bleeding after thrombolysis and improve the prognosis. |
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