| 肖维霞,马金珠.监测血清β-hCG下降时间用于指导妊娠滋养细胞疾病化疗方案的意义.[J].中南医学科学杂志.,2019,(1):61-63. |
| 监测血清β-hCG下降时间用于指导妊娠滋养细胞疾病化疗方案的意义 |
| Clinical efficacy of monitoring serum beta-hCG fall time in guiding chemotherapy regimens for gestational trophoblastic disease |
| 投稿时间：2018-08-29 修订日期：2018-10-24 |
| DOI：10.15972/j.cnki.43-1509/r.2019.01.016 |
| 中文关键词: 滋养细胞疾病 下降时间 血清β-hCG 化疗方案 临床效果 |
| 英文关键词:trophoblastic diseases falling time beta hCG serum chemotherapy regimens clinical effects |
| 基金项目: |
|
| 摘要点击次数: 644 |
| 全文下载次数: 575 |
| 中文摘要: |
| 分析血清β-hCG下降时间指导妊娠滋养细胞疾病(GTD)化疗的意义。选择GTD化疗患者,分析患者β-hCG及经阴道多普勒超声检查结果。GTD良性组在化疗前及前2个疗程化疗阶段,血清β-hCG水平均显著低于GTD恶性组；GTD良性组与恶性组不同化疗阶段血清β-hCG水平总体呈下降趋势,且不同疗程之间的血清β-hCG水平均存在统计学差异；不同化疗疗程阶段血清β-hCG与PSV、EDV水平总体呈负相关,与阻力指数则总体呈正相关。本研究认为血清β-hCG下降时间与其接受化疗的周期和取得的疗效均存在较好的相关性,因此监测血清β-hCG下降时间用于指导GTD化疗方案具有一定的可行性。 |
| 英文摘要: |
| it is to analyze the significance of serum-hCG decrease in guiding gestational trophoblastic disease (GTD) chemotherapy. Patients with GTD chemotherapy were selected to analyze the results of beta-hCG and transvaginal Doppler ultrasound. The levels of serum beta-hCG in GTD benign group were significantly lower than those in GTD malignant group before and during the first two courses of chemotherapy; the levels of serum beta-hCG in GTD benign group and malignant group at different stages of chemotherapy showed a general downward trend, and the levels of serum beta-hCG in different courses of chemotherapy were statistically different. During the course of chemotherapy, serum beta-hCG was negatively correlated with PSV and EDV levels, and positively correlated with resisitant index. This study suggests that the time of serum beta-hCG decline is correlated with the cycle of chemotherapy and the efficacy of chemotherapy. Therefore, it is feasible to monitor the time of serum beta-hCG decline in GTD chemotherapy. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
| 关闭 |