| 甄海旭,刘建文,李振.网膜素、血清HCY与急性冠脉综合征的相关性研究.[J].中南医学科学杂志.,2019,(1):44-46, 51. |
| 网膜素、血清HCY与急性冠脉综合征的相关性研究 |
| Study on the correlation between serum HCY and prognosis in patients with acute coronary syndrome |
| 投稿时间：2018-09-13 修订日期：2018-12-18 |
| DOI：10.15972/j.cnki.43-1509/r.2019.01.011 |
| 中文关键词: 网膜素 血清同型半胱氨酸 急性冠脉综合征 预后 相关性 |
| 英文关键词:retinal serum homocysteine acute coronary syndrome prognosis correlation |
| 基金项目: |
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| 中文摘要: |
| 本研究通过检测100例急性冠脉综合征(ACS)患者和50例正常体检人员的网膜素和同型半胱氨酸(Hcy)水平,发现ACS患者的肌酐、Hcy、心肌肌钙蛋白I(cTnI)、肌酸激酶同工酶(CK-MB)、超敏C反应蛋白(hs-CRP)、网膜素-1指标均显著高于常人；BMI、hs-CRP、Hcy及网膜素-1是导致ACS的相关因素；网膜素-1浓度的降低与hs-CRP、Hcy浓度的升高都是造成ACS的独立因素。结果说明,网膜素-1与Hcy可能是介导ACS发生的独立因素,将这两种物质作为不稳定的斑块进行评估和预测指标有重要价值。 |
| 英文摘要: |
| In this study, the retinal and HCY levels of 100 ACS patients and 50 normal physical examination staff were tested, and the analysis found that levels of creatinine, Hcy, cTnI, CK-MB, hs-CRP and retinin-1 in patients with ACS were significantly higher than those in normal controls. The levels of BMI, hs-CRP, Hcy and omentum-1 were the related factors leading to ACS. The decrease of ovalbumin-1 and the increase of hs-CRP and Hcy concentrations were independent factors of ACS. The results suggesting ovalbumin-1 and Hcy may be independent factors that mediate the occurrence of ACS. Retinal-1 and Hcy may have an important value for early screening, the assessment and prediction of unstable plaques. |
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