| 范雪娇.呼吸道感染儿童鼻咽抽吸物和BALF的病原学差异分析.[J].中南医学科学杂志.,2016,(5):523-526. |
| 呼吸道感染儿童鼻咽抽吸物和BALF的病原学差异分析 |
| Etiological Analysis of NPA and BALF in Children withRespiratory Tract Infection |
| 投稿时间：2016-02-18 修订日期：2016-06-27 |
| DOI： |
| 中文关键词: 呼吸道感染 鼻咽抽吸物 肺泡灌洗液 病原体 |
| 英文关键词:respiratory tract infection nasopharyngeal aspiration(NPA) bronchoalveolar lavage fluid(BALF) pathogen |
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| 中文摘要: |
| 目的 呼吸道感染儿童鼻咽抽吸物(NPA)和肺泡灌洗液(BALF)的病原学差异分析。方法采集本院儿科住院治疗的急性呼吸道感染的140例患儿的NPA和BALF,比较NPA和BALF中各病原体检出率和不同疾病患者各病原体检出率的差异,以及NPA和BALF中各病原体单纯感染率和混合感染率的差异。结果与BALF相比,NPA中细菌检出率(17.14% vs 8.57%)和非典型病原体检出率(84.29% vs 69.29%)分别高于BALF(P均<0.05)；NPA中病毒检出率低于BALF中的检出率(6.43% vs 14.29%)。NPA中非典型病原体的单纯感染高于混合感染(45.0% vs 12.86%)；BALF中非典型病原体的单纯感染高于混合感染(50.71% vs 18.57%)(P<0.05)。肺炎患者的细菌、病毒、非典型病原体检出率均高于支气管炎、毛细支气管炎患者(P<0.05)。结论鼻咽抽吸物中细菌和非典型病原体的检出率高于肺泡灌洗液,病毒的检出率低于肺泡灌洗液,肺炎中病原体的检出率高于支气管炎、毛细支气管炎患者。 |
| 英文摘要: |
| Objective To make etiological analysis of nasopharyngeal aspiration(NPA) and bronchialveolarlavage fluid(BALF) in children with respiratory tract infection.MethodsCollected NPA and BALF from 140 cases of children with acute respiratory tract infection in our hospital,and compared the differences of pathogenic examination rate in NPA and BALF.Compared the differences of pathogenic infection rate among different diseases,and the difference of the simple pathogens infection rate and the mixed pathogens infection rate in NPA and BALF.ResultsThe bacterial detection rate in NPA was higher than that in BALF(17.14% vs 8.57%);The virus detection rate in NPAwas lower than that in BALF(6.43% vs 14.29%)；The rate of atypical pathogen examination in NPA was higher than that in BALF(84.29% vs 69.29%) (all P<0.05).The simple atypical pathogens infection ratein BALF was higher than that of mixed infection(50.71% vs 18.57%),the simple atypical pathogens infection rate in NPA was higher than that of mixed infection(45% vs 12.86%),and the rate of bacterial,viral and atypical pathogens in pneumonia patients were higher than those in bronchitis and bronchiolitis patients (all P<0.05).ConclusionThe detection rate of bacteria and viruses in NPA was higher than that in BALF,but the detection rate of atypical pathogens was lower than that of BALF,the detection rate of pathogens in patients with pneumonia was higher than that in patients with bronchitis and bronchiolitis. |
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