王湘江,汤勇智,刘春磊,王贵清,杨立群,黎昭华,侯翰涛,陈勇.PVP治疗合并COPD的胸腰椎压缩性骨折患者术后肺功能改善的研究.[J].中南医学科学杂志.,2016,(4):376-378, 456.
PVP治疗合并COPD的胸腰椎压缩性骨折患者术后肺功能改善的研究
Influence of Pulmonary Function for Chronic Obstructive Pulmonary Disease(COPD) Patients with Thoracolumbar Osteoporotic Vertebral Compression Fractures After Percutaneous Vertebroplasty (PVP)
投稿时间:2016-02-25  修订日期:2016-05-28
DOI:
中文关键词:  经皮椎体成形术  慢性阻塞性肺疾病  肺功能
英文关键词:PVP  COPD  pulmonary function
基金项目:
作者单位
王湘江 清远市人民医院,广州医科大学附属第六医院,广东 清远 511518 
汤勇智 清远市人民医院,广州医科大学附属第六医院,广东 清远 511518 
刘春磊 清远市人民医院,广州医科大学附属第六医院,广东 清远 511518 
王贵清 清远市人民医院,广州医科大学附属第六医院,广东 清远 511518 
杨立群 清远市人民医院,广州医科大学附属第六医院,广东 清远 511518 
黎昭华 清远市人民医院,广州医科大学附属第六医院,广东 清远 511518 
侯翰涛 清远市人民医院,广州医科大学附属第六医院,广东 清远 511518 
陈勇 清远市人民医院,广州医科大学附属第六医院,广东 清远 511518 
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中文摘要:
      目的 研究经皮椎体成形术(PVP)治疗慢性阻塞性肺疾病(COPD)合并骨质疏松性单节段胸腰椎压缩性骨折患者肺功能变化。方法对38例COPD合并单节段骨质疏松性胸腰椎压缩性骨折患者进行了椎体成形术,分别测量术前及术后1周、3月及12个月后患者肺功能、VAS评分及活动能力评分,统计分析患者术前、术后的变化。结果PVP术后患者VAS评分及活动能力评分降低,术后1周显著降低,并且随着时间推移评分逐渐降低。患者手术前后肺活量(VC)、用力肺活量(FVC)、第一秒钟用力呼气容积(FEV1)及最大分钟通气量(MVV)间差异存在显著性(P<0.05)。术前及术后VAS评分与活动能力评分改善值之间,VAS评分与各肺功能指标改善值之间存在显著正相关性(P<0.05)。结论PVP术后COPD的单节段骨质疏松性胸腰压缩性骨折患者疼痛明显缓解,活动能力及肺功能得到改善。
英文摘要:
      Objective To investigate the changes of respiratory function in patients affected by chronic obstructive pulmonary disease(COPD) with single thoracolumbar osteoporotic vertebral compression fractures treated with vertebroplasty(PVP).MethodsThirty-eight patients affected by COPD and single thoracolumbar osteoporotic vertebral compression fractures underwent PVP.VAS scores,mobility scores and pulmonary function were measured for all patient before and one week,three months,twelve months after PVP.Statistic sofeware was used to analyse the preoperative and postoperative changes.ResultsA significant VAS-score decrease was observed 1 week after PVP,with a subsequent decrease overtime;A significant variation (P<0.05)was observed between the VAS score values,VC,FVC,FEV1 and MVV values before the procedure and after treatment.A significant correlation was observed between improvement of VAS-score values and mobility scores,and improvement of VAS-score values and the pulmonary function indexes.ConclusionsPVP can significantly release pain and improve pulmonary function and mobility in patients with moderate and severe COPD affected by single thoracolumbar osteoporotic vertebral compression fractures.
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