| 吴秀镯,刘雪凯.酒精性肝病患者血清CA125检测结果分析.[J].中南医学科学杂志.,2016,(3):306-308. |
| 酒精性肝病患者血清CA125检测结果分析 |
| Analysis on the Results of CA 125 in Serum of Patients withAlcoholic Liver Disease |
| 投稿时间：2015-12-03 修订日期：2016-03-20 |
| DOI： |
| 中文关键词: CA125 酒精性肝病 酒精性脂肪肝 肝硬化 |
| 英文关键词:Cancer antigen 125 Alcoholic liver disease Alcoholic fatty liver Cirrhosis |
| 基金项目: |
|
| 摘要点击次数: 595 |
| 全文下载次数: 590 |
| 中文摘要: |
| 目的 分析酒精性肝病患者血清CA125的水平变化,探讨血清CA125在酒精性肝病中的应用价值。方法本文共收集肝病患者96例,将其分为非酒精性脂肪肝组24例,酒精性脂肪肝组10例,肝炎后肝硬化组37例和酒精性肝硬化组25例,另22例健康体检者作为健康对照组,测定各组血清CA125的水平。结果酒精性脂肪肝组、肝炎后肝硬化组和酒精性肝硬化组CA125水平均明显高于健康对照组(P<0.05),CA125异常的病例数及百分数也明显高于健康对照组,酒精性脂肪肝组CA125水平高于非酒精性脂肪肝组(P<0.05)。非酒精性脂肪肝组与健康对照组,酒精性肝硬化组与肝炎后肝硬化组间CA125水平差异均无显著性(P>0.05)。结论血清CA125在酒精性肝病患者中随着肝脏病变的加重有不同程度的改变,早期酒精性脂肪肝时CA125已呈现升高趋势,CA125在酒精性肝病诊治及预后中具有一定的临床应用价值。 |
| 英文摘要: |
| Objective To analyse the results of CA 125 in serum of patients with alcoholic liver disease,and investigate the application value of CA125 in alcoholic liver disease.MethodsA total of 96 patients with liver disease and 22 healthy people as normal control group were studied,and the patients were divided into alcoholic and non-alcoholic fatty liver group,post-hepatitis liver cirrhosis group and alcoholic liver cirrhosis group.Serum CA125 levels were determined using routine laboratory methods.ResultsSerum CA125 in alcoholic fatty liver group,post-hepatitis liver cirrhosis group and alcoholic cirrhosis group were respectively,significantly higher than that of normal group (P<0.05),and the number of abnormal CA125 cases was respectively,significantly higher than that of normal group as well as the percentage.Serum CA125 in alcoholic fatty liver group was significantly higher than that of non-alcoholic fatty liver group (P<0.05).There was no striking difference between the lever of serum CA125 in non-alcoholic fatty liver and that of normal group(P>0.05),similarly,there was not much difference between both groups of liver cirrhosis (P>0.05).ConclusionSerum CA125 of patients with alcoholic liver disease has different levels of expression with exacerbations.It has been showing an increasing trend during the early stage of alcoholic fatty liver.There is some clinical value of CA125 in alcoholic liver disease. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
| 关闭 |
|
|
|