| 苏华,谢睿彬.血清Cys-C、血脂及胆红素与冠脉硬化程度的关系分析.[J].中南医学科学杂志.,2016,(1):67-70. |
| 血清Cys-C、血脂及胆红素与冠脉硬化程度的关系分析 |
| Analysis of Correlation Between Serum Cys-C,Blood Lipid,BilirubinLevel and Severity of Coronary Atherosclerosis |
| 投稿时间：2015-11-02 修订日期：2016-01-05 |
| DOI： |
| 中文关键词: 胱抑素C 血脂 胆红素 冠状动脉粥样硬化 评估 |
| 英文关键词:cystatin C blood lipid bilirubin coronary atherosclerosis assess |
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| 中文摘要: |
| 目的 探讨血清胱抑素(Cys-C)、血脂与胆红素与冠状动脉粥样硬化严重程度的关系。方法 选取2013年9月~2015年9月于我院诊治的冠心病患者335例,根据冠脉造影术确定冠脉狭窄支数,其中单支狭窄组133例、两支狭窄组115例、多支狭窄组87例。另选取无冠脉狭窄者85例作为正常对照组。比较四组患者血清胱抑素C、血脂与胆红素水平。结果与正常对照组相比,单支狭窄组、两支狭窄组、多支狭窄组患者Cys-C、总胆固醇、三酰甘油、低密度脂蛋白胆固醇水平较高,高密度脂蛋白胆固醇、总胆红素、直接胆红素、间接胆红素水平较低(P<0.05)；与单支狭窄组相比,两支狭窄组、多支狭窄组患者Cys-C、总胆固醇、三酰甘油、低密度脂蛋白胆固醇水平较高,高密度脂蛋白胆固醇、总胆红素、直接胆红素、间接胆红素水平较低(P<0.05)。结论除血脂外,可应用血清Cys-C及胆红素对冠状动脉粥样硬化严重程度进行评估,以指导冠心病的诊疗。 |
| 英文摘要: |
| Objective To explore the relevance between Serum Cys-C,blood lipid,bilirubin level and severity of coronary atherosclerosis.Method335 patients with coronary heart disease in our hospital from September 2013 to September 2015 were divided into single stenosis group(n=133),double stenosis group(n=115) and multiple stenosis group(n=87) according to coronary angiography.85 patients without coronary stenosis were selected into normal control group.Serum cystatin C,blood lipid,bilirubin level were compared between four groups.ResultCompared to the normal control group,patients in the single stenosis group,double stenosis group and multiple stenosis group had higher cystatin C,total cholesterol,triacylglycerol,low density lipoprotein cholesterol level and had lower high density lipoprotein cholesterol,total bilirubin,direct bilirubin,indirect bilirubin level(P<0.05).Compared to the single stenosis group,patients in the double stenosis group and multiple stenosis group had higher cystatin C,total cholesterol,triacylglycerol,low density lipoprotein cholesterol level and had lower high density lipoprotein cholesterol,total bilirubin,direct bilirubin,indirect bilirubin level(P<0.05).ConclusionSerum cystatin C and bilirubin level can be used to assess the severity of coronary atherosclerosis except blood lipid and to guide the diagnosis and treatment of coronary heart disease. |
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